Processing

Please wait...

Settings

Settings

Goto Application

1. WO2008089278 - BIOLOGICALLY DERIVED ROBOTS AND THEIR USE

Publication Number WO/2008/089278
Publication Date 24.07.2008
International Application No. PCT/US2008/051221
International Filing Date 16.01.2008
IPC
C12N 1/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
C12N 1/20 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
C12N 1/36 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
36Adaptation or attenuation of cells
CPC
C07K 14/245
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
24from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245Escherichia (G)
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US] (AllExceptUS)
  • WALTER, Jessica, M. [US]/[US] (UsOnly)
  • GREENFIELD, Derek [US]/[US] (UsOnly)
  • BUSTAMANTE, Carlos [US]/[US] (UsOnly)
  • LIPHARDT, Jan, T. [DE]/[US] (UsOnly)
Inventors
  • WALTER, Jessica, M.
  • GREENFIELD, Derek
  • BUSTAMANTE, Carlos
  • LIPHARDT, Jan, T.
Agents
  • ULLSPERGER, Chris, J.
Priority Data
60/885,38917.01.2007US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIOLOGICALLY DERIVED ROBOTS AND THEIR USE
(FR) ROBOTS À DÉRIVATION BIOLOGIQUE ET LEUR UTILISATION
Abstract
(EN)
The invention provides biologically-derived robots or 'biobots' which can be remotely controlled, e.g., by signaling with light, and programmed to perform a variety of synthesis, assembly, repair, and monitoring tasks. Biobots can perform many of the functions of microbes, including moving through viscous environments, tracking chemical gradients, producing proteins, and synthesizing small molecules. Biobots can be frozen and thawed with little loss of activity, and have lifetimes of 24 hours or more. In some embodiments, the biobots are inherently safe since they contain no genome (or a limited 'minigenome') and cannot self-replicate. These cellular automata should be useful for assisting workers in the defense, energy, medical and computing industries.
(FR)
Robots à dérivation biologique, ou 'biobots', susceptibles d'être télécommandés, par exemple par signalisation lumineuse, et programmés pour une gamme d'opérations de synthèse, d'assemblage, de réparation et de surveillance. Les biobots peuvent remplir un grand nombre de fonctions propres aux microbes, y compris le déplacement dans des environnements visqueux, la détection de gradients chimiques, la production de protéines, et la synthèse de petites molécules. On peut congeler et décongeler les biobots, en subissant une faible perte d'activité et en conservant une durée de vie de 24 heures ou plus. Selon certaines variantes, les biobots sont intrinsèquement sûrs car ils ne contiennent pas de génome (ou ils contiennent un 'minigénome' limité) et ils sont incapables de duplication. Ces automates cellulaires devraient être utiles dans un rôle d'assistance aux travailleurs des secteurs de la défense, de l'énergie, de la médecine et de l'informatique.
Latest bibliographic data on file with the International Bureau