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1. WO2008074067 - DETECTION AND QUANTIFICATION OF POLYPEPTIDES USING MASS SPECTROMETRY

Publication Number WO/2008/074067
Publication Date 26.06.2008
International Application No. PCT/AU2007/001951
International Filing Date 18.12.2007
Chapter 2 Demand Filed 22.09.2008
IPC
G01N 27/62 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
62by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
G01N 33/48 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
H01J 49/26 2006.1
HELECTRICITY
01BASIC ELECTRIC ELEMENTS
JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
49Particle spectrometers or separator tubes
26Mass spectrometers or separator tubes
CPC
G01N 33/6848
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6803General methods of protein analysis not limited to specific proteins or families of proteins
6848Methods of protein analysis involving mass spectrometry
H01J 49/0036
HELECTRICITY
01BASIC ELECTRIC ELEMENTS
JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
49Particle spectrometers or separator tubes
0027Methods for using particle spectrometers
0036Step by step routines describing the handling of the data generated during a measurement
H01J 49/26
HELECTRICITY
01BASIC ELECTRIC ELEMENTS
JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
49Particle spectrometers or separator tubes
26Mass spectrometers or separator tubes
Applicants
  • MACQUARIE UNIVERSITY [AU]/[AU] (AllExceptUS)
  • ASHMAN, Keith [AU]/[AU] (UsOnly)
  • MCKAY, Matthew [AU]/[AU] (UsOnly)
  • SHERMAN, James [AU]/[AU] (UsOnly)
  • MOLLOY, Mark [AU]/[AU] (UsOnly)
Inventors
  • ASHMAN, Keith
  • MCKAY, Matthew
  • SHERMAN, James
  • MOLLOY, Mark
Agents
  • FREEHILLS PATENT & TRADE MARK ATTORNEYS
Priority Data
200690701718.12.2006AU
60/885,37317.01.2007US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DETECTION AND QUANTIFICATION OF POLYPEPTIDES USING MASS SPECTROMETRY
(FR) DÉTECTION ET QUANTIFICATION DE POLYPEPTIDES PAR SPECTROMÉTRIE DE MASSE
Abstract
(EN)
The invention relates to the detection and quantification of polypeptides using mass spectrometry. Specifically, the invention provides a method for testing whether a target polypeptide is present in a sample of a set of polypeptides, a method for deriving a 5 value for distinguishing polypeptides of a set of polypeptides from each other, a database containing values for distinguishing each polypeptide of a set of polypeptides from each other, and an apparatus for configuring a mass scan of a mass spectrometer to test whether a target polypeptide of a set of polypeptides is present in a sample of the set.
(FR)
Cette invention concerne la détection et la quantification de polypeptides par spectrométrie de masse. Elle concerne en particulier: un procédé permettant de déterminer par un test si un polypeptide cible est présent dans un échantillon d'un ensemble de polypeptides, et d'en dériver une valeur utilisable pour distinguer un polypeptide d'un autre dans ensemble de polypeptides; une base de données contenant des valeurs qui permettent de distinguer un polypeptide d'un autre dans ensemble de polypeptides; et un appareil qui permet de configurer un balayage en masse d'un spectromètre de masse en vue de déterminer par un test si un polypeptide cible d'un ensemble de polypeptides est présent dans un échantillon de l'ensemble.
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