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1. (WO2008063662) GOLD (III) CHLORIDE COMPOSITIONS FOR CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2008/063662 International Application No.: PCT/US2007/024343
Publication Date: 29.05.2008 International Filing Date: 21.11.2007
IPC:
A61K 33/24 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
Applicants:
GUTIERREZ, Sergio, T. [US/US]; US (UsOnly)
BLACK LION PHARMACEUTICALS [US/US]; 2576 Island Palm Court San Jose, CA 95133, US (AllExceptUS)
Inventors:
GUTIERREZ, Sergio, T.; US
Priority Data:
60/860,58121.11.2006US
Title (EN) GOLD (III) CHLORIDE COMPOSITIONS FOR CANCER
(FR) COMPOSITIONS À BASE DE CHLORURE D'OR (III) DANS LE TRAITEMENT DU CANCER
Abstract:
(EN) Methods and compositions for therapy of cancer are provided. Compositions comprising therapeutically effective amounts of gold(III) chloride are provided. Anti-proliferative, apoptotic and cytotoxic effects of specific gold(III) chlorides, such as hydrogen tetrachloroaurate and auric acid, are disclosed. Methods for preparation of gold(III) chlorides having anti-cancer effects are provided. Methods and compositions for therapy, treatment and prevention of cancer comprising gold(III) chlorides are provided. Methods for preparing copositions that induce apoptosis by the caspase pathway are provided.
(FR) Procédés et compositions utilisés dans le traitement du cancer. L'invention propose des compositions comprenant des quantités thérapeutiquement efficaces de chlorure d'or (III). Les effets antiproliférateurs, apoptotiques et cytotoxiques de chlorures d'or (III) spécifiques, comme le tétrachloroaurate d'hydrogène et l'acide aurique sont décrits. L'invention propose des procédés de préparation de chlorures d'or (III) ayant des effets anticancéreux. L'invention propose également des procédés et des compositions utilisés dans le traitement et la prévention du cancer et comprenant des chlorures d'or (III). L'invention propose par ailleurs des procédés de préparation de compositions qui induisent l'apoptose par la voie des caspases.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)