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1. (WO2008063644) METHOD OF RADIO-SENSITIZING TUMORS USING A RADIO-SENSITIZING AGENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2008/063644 International Application No.: PCT/US2007/024271
Publication Date: 29.05.2008 International Filing Date: 20.11.2007
IPC:
A61K 31/00 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
CEPHALON, INC. [US/US]; 41 Moores Road P.O. Box 4011 Frazer, PA 19355, US (AllExceptUS)
DIEBOLD, James, L. [US/US]; US (UsOnly)
HUDKINS, Robert, L. [US/US]; US (UsOnly)
MIKNYOCZKI, Sheila, J. [US/US]; US (UsOnly)
RUGGERI, Bruce [US/US]; US (UsOnly)
Inventors:
DIEBOLD, James, L.; US
HUDKINS, Robert, L.; US
MIKNYOCZKI, Sheila, J.; US
RUGGERI, Bruce; US
Agent:
LARSEN, Scott, K.; Caphalon, Inc. 41 Moores Road P.O. Box 4011 Frazer, PA 19355, US
Priority Data:
60/860,03620.11.2006US
Title (EN) METHOD OF RADIO-SENSITIZING TUMORS USING A RADIO-SENSITIZING AGENT
(FR) PROCÉDÉ DE RADIOSENSIBILISATION DES TUMEURS À L'AIDE D'UN AGENT RADIOSENSIBILISATEUR
Abstract:
(EN) The present invention relates to a method of treating cancer using PARP inhibitors as radio-sensitization agents of tumors. Specifically the present invention relates to a method of radio-sensitization of tumors using a compound of Formula (I) or a pharmaceutically acceptable salt form thereof. The present invention also relates to a pharmaceutical compositions of PARP inhibitors for radiosensitizing tumors.
(FR) Cette invention concerne un procédé permettant de traiter le cancer en utilisant des inhibiteurs de PARP comme agents de radiosensibilisation des tumeurs. De manière spécifique, l'invention concerne un procédé de radiosensibilisation des tumeurs en utilisant un composé de formule (I) ou son sel pharmaceutiquement acceptable. L'invention concerne par ailleurs des compositions pharmaceutiques d'inhibiteurs de PARP destinées à radiosensibiliser les tumeurs.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL198519AR063869MXMX/a/2009/005292CL33312007EP2086525JP2010510312
ES2352817CN101784268CA2671517PT2086525NZ576693AU2007321987
AU2014200040IN3561/CHENP/2009