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1. WO2008062013 - PREPARATION OF 4-SUBSTITUTED 2-AMINO-BENZO[4,5]FURO [3,2-D]PYRIMIDINE DERIVATIVES

Publication Number WO/2008/062013
Publication Date 29.05.2008
International Application No. PCT/EP2007/062632
International Filing Date 21.11.2007
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C07D 491/04 (2006.01)
CPC
C07D 491/04
Applicants
  • CELLZOME LIMITED [GB/GB]; Chesterford Research Park Little Chesterford Cambridgeshire CB10 1XL, GB (AllExceptUS)
  • JONES, Alison [GB/GB]; GB (UsOnly)
  • WILSON, Francis [GB/GB]; GB (UsOnly)
  • DYKE, Hazel [GB/GB]; GB (UsOnly)
  • PRICE, Steven [GB/GB]; GB (UsOnly)
  • CRAMP, Sue [GB/GB]; GB (UsOnly)
  • SZABO, Andras [HU/HU]; HU (UsOnly)
  • REPASI, Jozsef [HU/HU]; HU (UsOnly)
Inventors
  • JONES, Alison; GB
  • WILSON, Francis; GB
  • DYKE, Hazel; GB
  • PRICE, Steven; GB
  • CRAMP, Sue; GB
  • SZABO, Andras; HU
  • REPASI, Jozsef; HU
Agents
  • HUHN, Michael; Isenbruck Bösl Hörschler Wichmann Huhn LLP Theodor-Heuss-Anlage 12 68165 Mannheim, DE
Priority Data
06124539.522.11.2006EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PREPARATION OF 4-SUBSTITUTED 2-AMINO-BENZO[4,5]FURO [3,2-D]PYRIMIDINE DERIVATIVES
(FR) PRÉPARATION DE DÉRIVÉS DE 2-AMINO-BENZO[4,5]FURO [3,2-D]PYRIMIDINE SUBSTITUÉS EN POSITION 4
Abstract
(EN)
The present invention is directed to a process for the preparation of a compound of formula (I), wherein R1, R2 and X have the meaning as indicated in the description and claims. Said compounds are useful as key intermediates for the preparation of the related pharmaceutically active compounds or as active compounds.
(FR)
La présente invention concerne un procédé de préparation d'un composé de formule (I), dans laquelle R1, R2 et X ont le sens qui est indiqué dans la description et les revendications. Lesdits composés sont utilisables en tant qu'intermédiaires clés pour la préparation des composés pharmaceutiquement actifs apparentés ou en tant que composés actifs.
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