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1. (WO2008059349) METHOD OF FLUORINE-18 LABELLING OF TROPANE DERIVATIVES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2008/059349 International Application No.: PCT/IB2007/003476
Publication Date: 22.05.2008 International Filing Date: 13.11.2007
IPC:
C07D 451/02 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
451
Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
02
containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane; Cyclic acetals thereof
Applicants:
ORPHACHEM [FR/FR]; Rue Montalembert Centre d'Accueil Entreprises - Unité INSERM 484 F-63000 Clermont-Ferrand, FR (AllExceptUS)
DOLLE, Frédéric [FR/FR]; FR (UsOnly)
EMOND, Patrick [FR/FR]; FR (UsOnly)
LE GAILLIARD, Joël [FR/FR]; FR (UsOnly)
HINNEN, Françoise [FR/FR]; FR (UsOnly)
HELFENBEIN, Julie [FR/FR]; FR (UsOnly)
Inventors:
DOLLE, Frédéric; FR
EMOND, Patrick; FR
LE GAILLIARD, Joël; FR
HINNEN, Françoise; FR
HELFENBEIN, Julie; FR
Agent:
COLOMBET, Alain; Cabinet Lavoix 2, place d'Estienne d'Orves F-75441 Paris Cedex 09, FR
Priority Data:
06291762.014.11.2006EP
60/865,69414.11.2006US
Title (EN) METHOD OF FLUORINE-18 LABELLING OF TROPANE DERIVATIVES
(FR) PROCÉDÉ DE MARQUAGE PAR LE FLUOR-18 DE DÉRIVÉS DU TROPANE
Abstract:
(EN) The invention relates to a one-step [18F]radiolabelling process of tropanamine derivatives which are useful for imaging the neuronal dopamine transporter (DAT) with Positron Emission Tomography (PET).
(FR) L'invention porte sur un procédé de radiomarquage par [18F] en une étape des dérivés de tropanamine, qui sont utiles pour visualiser le transporteur de dopamine neuronal (DAT) à l'aide de la tomographie à émission de positons (PET).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)