WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |

Search International and National Patent Collections
World Intellectual Property Organization
Machine translation
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/045107    International Application No.:    PCT/US2006/046236
Publication Date: 17.04.2008 International Filing Date: 01.12.2006
A61K 9/00 (2006.01)
Applicants: UNIVERSITY OF MASSACHUSETTS LOWELL [US/US]; 1 University Avenue, Lowell, Massachusetts 01854 (US) (For All Designated States Except US).
EDELSON, Jonathan [US/US]; (US) (For US Only).
NICOLOSI, Robert [US/US]; (US) (For US Only)
Inventors: EDELSON, Jonathan; (US).
NICOLOSI, Robert; (US)
Agent: DECONTI, Giulio, A., Jr.; Lahive & Cockfield, LLP, One Post Office Square, Boston, MA 02109-2127 (US)
Priority Data:
60/741,139 01.12.2005 US
Abstract: front page image
(EN)The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.
(FR)L'invention concerne des nanoémulsions contenant des toxines botuliniques. Dans un mode de réalisation, les nanoémulsions sont obtenues par microfluidisation haute pression et elles présentent une distribution granulométrique comprise exclusivement entre 10 et 300 nm. Les nanoémulsions selon l'invention sont utiles dans le traitement cosmétique et médical des états de contractures musculaires. Les toxines botuliniques peuvent, par exemple, détendre les muscles faciaux de sorte que les rides cutanées deviennent plus lisses et moins visibles. L'invention concerne également une préparation cosmétique pouvant être autoadministrée à domicile, sans surveillance médicale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)