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1. WO2008040984 - A REAGENT FORMULATION USING RUTHENIUM HEXAMINE AS A MEDIATOR FOR ELECTROCHEMICAL TEST STRIPS

Publication Number WO/2008/040984
Publication Date 10.04.2008
International Application No. PCT/GB2007/003772
International Filing Date 05.10.2007
IPC
C12Q 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
CPC
C12Q 1/004
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
001Enzyme electrodes
004mediator-assisted
Applicants
  • LIFESCAN SCOTLAND LIMITED [GB]/[GB] (AllExceptUS)
  • CARDOSI, Marco, F. [GB]/[GB] (UsOnly)
  • MILLS, Leanne [GB]/[GB] (UsOnly)
  • LEACH, Christopher, Philip [GB]/[GB] (UsOnly)
Inventors
  • CARDOSI, Marco, F.
  • MILLS, Leanne
  • LEACH, Christopher, Philip
Agents
  • TUNSTALL, Christopher, Stephen
Priority Data
60/850,22105.10.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A REAGENT FORMULATION USING RUTHENIUM HEXAMINE AS A MEDIATOR FOR ELECTROCHEMICAL TEST STRIPS
(FR) Formulation de réactif utilisant de l'HEXAMINE de RUTHéNIUM en tant que médiateur pour des bandes de tests électrochimiques
Abstract
(EN)
Described herein are various embodiments of a test strip, which may be capable of measuring an analyte. The test strip may include a working electrode and a reference electrode where the reagent formulation is disposed on the working electrode. The reagent formulation may be coated onto the test strip. The reagent formulation includes an enzyme, a ruthenium hexamine mediator, and a solution for dissolving the enzyme and the ruthenium hexamine mediator. The reagent formulation may be coated onto the test strip. The reagent formulation includes an enzyme, a ruthenium hexamine mediator, and a solution for dissolving the enzyme and the ruthenium hexamine mediator. The ruthenium hexamine has a concentration range from about 15% to about 20% (weight of mediator / volume) of solution. The enzyme may be either glucose oxidase and glucose dehydrogenase.
(FR)
La présente invention concerne divers modes de réalisation d'une bande de tests pouvant mesurer un analyte. Ladite bande peut comprendre une électrode de travail et une électrode de référence, la formulation de réactif étant disposée sur l'électrode de travail. La formulation du réactif peut être revêtue sur ladite bande et comprend une enzyme, un médiateur à base d'hexamine de ruthénium et une solution pour dissoudre l'enzyme et ledit médiateur. L'hexamine de ruthénium présente une plage de concentration d'environ 15 % à environ 20 % (poids du médiateur/volume) de la solution. L'enzyme peut être soit la glucose oxydase, soit la glucose déshydrogénase.
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