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Machine translation
1. (WO2008039553) SOLUBLE IL-17RCX4 AND METHODS OF USING IN INFLAMMATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/039553    International Application No.:    PCT/US2007/061909
Publication Date: 03.04.2008 International Filing Date: 09.02.2007
IPC:
C07K 14/15 (2006.01), C07K 16/28 (2006.01)
Applicants: ZYMOGENETICS, INC. [US/US]; 1201 Eastlake Avenue East, Seattle, WA 98102 (US) (For All Designated States Except US).
KUESTNER, Rolf, E. [US/US]; (US) (For US Only).
GAO, Zeren [US/US]; (US) (For US Only).
LEVIN, Steven, D. [US/US]; (US) (For US Only).
RIXON, Mark, W. [US/US]; (US) (For US Only)
Inventors: KUESTNER, Rolf, E.; (US).
GAO, Zeren; (US).
LEVIN, Steven, D.; (US).
RIXON, Mark, W.; (US)
Agent: ADAMS, Robyn; 1201 Eastlake Avenue East, Seattle, WA 98102 (US)
Priority Data:
60/772,177 10.02.2006 US
60/781,078 10.03.2006 US
Title (EN) SOLUBLE IL-17RCX4 AND METHODS OF USING IN INFLAMMATION
(FR) IL-17RCX4 SOLUBLE ET PROCÉDÉS D'UTILISATION DANS L'INFLAMMATION
Abstract: front page image
(EN)The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL- 17F, IL- 17 A, or both IL- 17A and IL- 17F polypeptide molecules. IL-17A and IL- 17F are cytokines that are involved in inflammatory processes and human disease. IL-17RC is a common receptor for IL- 17A and IL- 17F. The present invention includes methods of using a soluble IL- 17RC receptor, IL- 17RCx4 for treating inflammation.
(FR)La présente invention concerne le blocage, l'inhibition, la réduction, l'antagonisme ou la neutralisation de l'activité de molécules polypeptidiques IL-17F, IL-17A ou à la fois IL-17A et IL-17F. Les IL-17A et IL-17F sont des cytokines qui sont impliquées dans les processus inflammatoires et dans des maladies humaines. IL-17RC est un récepteur ordinaire des IL-17A et IL-17F. La présente invention concerne des procédés d'utilisation d'un récepteur IL-17RC soluble, le IL-17RCx4, pour traiter l'inflammation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)