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1. WO2008037700 - METHODS FOR BREAST CANCER PROGNOSIS

Publication Number WO/2008/037700
Publication Date 03.04.2008
International Application No. PCT/EP2007/060143
International Filing Date 25.09.2007
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
C12Q 2600/112
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
112Disease subtyping, staging or classification
C12Q 2600/118
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
118Prognosis of disease development
Applicants
  • SIEMENS HEALTHCARE DIAGNOSTICS GMBH [DE]/[DE] (AllExceptUS)
  • GEHRMANN, Mathias [DE]/[DE] (UsOnly)
  • VON TÖRNE, Christian [DE]/[DE] (UsOnly)
Inventors
  • GEHRMANN, Mathias
  • VON TÖRNE, Christian
Agents
  • MAIER, Daniel
Priority Data
06020209.027.09.2006EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR BREAST CANCER PROGNOSIS
(FR) PROCÉDÉS POUR PRONOSTIQUER UN CANCER DU SEIN
Abstract
(EN)
The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer in untreated breast cancer patients. More specific, the present invention relates to the prognosis of breast cancer based on measurements of the expression levels of marker genes in tumor samples of breast cancer patients. Marker genes are disclosed which allow for an accurate prognosis of breast cancer in patients having node negative, fast proliferating breast cancer.
(FR)
La présente invention concerne des procédés, des coffrets et des systèmes pour le pronostic du résultat de la maladie du cancer du sein chez des patientes atteintes d'un cancer du sein non traité. De façon plus précise, la présente invention concerne le pronostic d'un cancer du sein basé sur la mesure des taux d'expression de gènes marqueurs dans des échantillons de tumeur de patientes atteintes du cancer du sein. Des gènes marqueurs sont décrits, qui permettent un pronostic précis du cancer du sein chez des patientes ayant un cancer du sein à prolifération rapide, nodule négatif.
Also published as
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