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1. WO2008024485 - METHODS FOR TREATING CANCER COMPRISING THE ADMINISTRATION OF A VITAMIN D COMPOUND AND AN ADDITIONAL THERAPEUTIC AGENT

Publication Number WO/2008/024485
Publication Date 28.02.2008
International Application No. PCT/US2007/018770
International Filing Date 23.08.2007
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
59
Compounds containing 9,10-seco-cyclopenta[a]hydro- phenanthrene ring systems
592
9,10-Secoergostane derivatives, e.g. ergocalciferol, vitamin D2
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
59
Compounds containing 9,10-seco-cyclopenta[a]hydro- phenanthrene ring systems
593
9,10-Secocholestane derivatives, e.g. cholecalciferol, vitamin D3
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57
substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573
substituted in position 21, e.g. cortisone, dexamethasone, prednisone
A61P 35/00 (2006.01)
A61K 31/592 (2006.01)
A61K 31/593 (2006.01)
A61K 31/573 (2006.01)
CPC
A61K 31/337
A61K 31/573
A61K 31/59
A61K 31/593
A61K 45/06
Applicants
  • COUGAR BIOTECHNOLOGY, INC. [US/US]; 10990 Wilshire Blvd. Suite 1200 Los Angeles, CA 90024, US (AllExceptUS)
  • AUERBACH, Alan, H. [US/US]; US (UsOnly)
  • BELLDEGRUN, Arie, S. [US/US]; US (UsOnly)
Inventors
  • AUERBACH, Alan, H.; US
  • BELLDEGRUN, Arie, S.; US
Agents
  • INSOGNA, Anthony, M. ; Jones Day 222 East 41st Street New York, NY 10017-6702, US
Priority Data
60/934,92425.08.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR TREATING CANCER COMPRISING THE ADMINISTRATION OF A VITAMIN D COMPOUND AND AN ADDITIONAL THERAPEUTIC AGENT
(FR) PROCÉDÉS SERVANT À TRAITER UN CANCER CONSISTANT À ADMINISTRER UN COMPOSÉ DE LA VITAMINE D ET UN AGENT THÉRAPEUTIQUE SUPPLÉMENTAIRE ET COMPOSITIONS LES CONTENANT
Abstract
(EN)
Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a vitamin D compound, such as seocalcitol, in combination with at least one additional therapeutic agent, such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising vitamin D compounds and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid, e.g., corticosteroid or more specifically, a glucocorticoid.
(FR)
L'invention concerne des procédés et compositions servant à traiter un cancer. Plus particulièrement, les procédés servant à traiter un cancer consistent à administrer un composé de la vitamine D en association avec au moins un agent thérapeutique supplémentaire, tel qu'un agent anticancéreux ou un stéroïde. En outre, l'invention concerne des compositions comprenant des composés de la vitamine D et au moins un agent thérapeutique supplémentaire, tel qu'un agent anticancéreux ou un stéroïde, par exemple un corticostéroïde ou plus précisément un glucocorticoïde.
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