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1. (WO2008022045) DIFFERENTIAL LABELING OF CELLS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2008/022045 International Application No.: PCT/US2007/075742
Publication Date: 21.02.2008 International Filing Date: 10.08.2007
IPC:
A01K 67/00 (2006.01) ,C12Q 1/68 (2006.01) ,C12N 15/00 (2006.01) ,C12N 5/00 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
K
ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67
Rearing or breeding animals, not otherwise provided for; New breeds of animals
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
Applicants:
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; 1705 El Cmaino Real Mail code 1850 Palo Alto, CA 94306, US (AllExceptUS)
UNIVERSITY OF CHICAGO; 5801 South Ellis Street Chicago, IL 60637, US (AllExceptUS)
POPKO, Brian [US/US]; US (UsOnly)
BALABANOV, Roumen [US/US]; US (UsOnly)
WATKINS, Trent [US/US]; US (UsOnly)
Inventors:
POPKO, Brian; US
BALABANOV, Roumen; US
WATKINS, Trent; US
Agent:
WONG, Karen, K. ; Wilson Sonsini Goodrich & Rosati 650 Page Mill Road Palo Alto, CA 94304-1050, US
Priority Data:
60/822,00110.08.2006US
Title (EN) DIFFERENTIAL LABELING OF CELLS
(FR) MARQUAGE DIFFÉRENTIEL DE CELLULES
Abstract:
(EN) The invention relates to the generation of an animal model that exhibits neural cell-specific expression of a marker gene that correlates to remyelination or myelin repair. The compositions and methods embodied in the present invention are particularly useful for drug screening and/or treatment of demyelination disorders, particularly in identifying compounds that promote or inhibit remyelination.
(FR) La présente invention concerne la génération d'un modèle animalier qui illustre l'expression spécifique de cellules neurales d'un gène marqueur correspondant à une remyélination ou une réparation de la myéline. Les compositions et procédés faisant l'objet de la présente invention se révèlent particulièrement utiles pour le criblage de médicaments et/ou le traitement de troubles de démyélination, particulièrement pour identifier des composés qui favorisent ou inhibent la remyélination.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL196803EP2049686JP2010500039CA2660321