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1. WO2008021927 - HEPATITIS C VIRUS INHIBITORS

Publication Number WO/2008/021927
Publication Date 21.02.2008
International Application No. PCT/US2007/075544
International Filing Date 09.08.2007
IPC
C07D 401/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14containing three or more hetero rings
C07D 403/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
14containing three or more hetero rings
A61P 31/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
A61K 31/4025 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
4025not condensed and containing further heterocyclic rings, e.g. cromakalim
A61K 31/4178 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4178not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
CPC
A61K 31/4025
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
4025not condensed and containing further heterocyclic rings, e.g. cromakalim
A61K 31/4164
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
41641,3-Diazoles
A61K 31/4178
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
41641,3-Diazoles
4178not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Applicants
  • BRISTOL-MYERS SQUIBB COMPANY [US]/[US] (AllExceptUS)
  • BACHAND, Carol [CA]/[CA] (UsOnly)
  • BELEMA, Makonen [ET]/[US] (UsOnly)
  • DEON, Daniel H. [CA]/[CA] (UsOnly)
  • GOOD, Andrew C. [GB]/[US] (UsOnly)
  • GOODRICH, Jason [US]/[US] (UsOnly)
  • JAMES, Clint A. [CA]/[US] (UsOnly)
  • LAVOIE, Rico [CA]/[US] (UsOnly)
  • LOPEZ, Omar D. [AR]/[US] (UsOnly)
  • MARTEL, Alain [CA]/[CA] (UsOnly)
  • MEANWELL, Nicholas A. [US]/[US] (UsOnly)
  • NGUYEN, Van N. [US]/[US] (UsOnly)
  • ROMINE, Jeffrey Lee [US]/[US] (UsOnly)
  • RUEDIGER, Edward H. [CA]/[CA] (UsOnly)
  • SNYDER, Lawrence B. [US]/[US] (UsOnly)
  • ST. LAURENT, Denis R. [US]/[US] (UsOnly)
  • YANG, Fukang [CN]/[US] (UsOnly)
  • LANGLEY, David R. [US]/[US] (UsOnly)
  • WANG, Gan [CN]/[US] (UsOnly)
  • HAMANN, Lawrence G. [US]/[US] (UsOnly)
Inventors
  • BACHAND, Carol
  • BELEMA, Makonen
  • DEON, Daniel H.
  • GOOD, Andrew C.
  • GOODRICH, Jason
  • JAMES, Clint A.
  • LAVOIE, Rico
  • LOPEZ, Omar D.
  • MARTEL, Alain
  • MEANWELL, Nicholas A.
  • NGUYEN, Van N.
  • ROMINE, Jeffrey Lee
  • RUEDIGER, Edward H.
  • SNYDER, Lawrence B.
  • ST. LAURENT, Denis R.
  • YANG, Fukang
  • LANGLEY, David R.
  • WANG, Gan
  • HAMANN, Lawrence G.
Agents
  • MINGO, Pamela A.
Priority Data
11/835,46208.08.2007US
60/836,99611.08.2006US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) HEPATITIS C VIRUS INHIBITORS
(FR) INHIBITEURS DU VIRUS DE L'HÉPATITE C
Abstract
(EN) The present disclosure relates to a compound of Formula (I), compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
(FR) La présente invention concerne des composés, des compositions et des méthodes pour le traitement d'une infection par le virus de l'hépatite C (VHC). L'invention concerne également des compositions pharmaceutiques contenant ces composés ainsi que des méthodes d'utilisation de ces composés dans le traitement d'une infection par le VHC.
Related patent documents
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