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1. WO2008021486 - USE OF ADSBORBENT CARBON MICROSPHERES (AST-120) TO TREAT GASTROESOPHOGEAL REFLUX DISEASE OR SYMPTOMS THEREOF

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Publication Number WO/2008/021486
Publication Date 21.02.2008
International Application No. PCT/US2007/018240
International Filing Date 16.08.2007
IPC
A61K 33/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
44Elemental carbon, e.g. charcoal, carbon black
A61K 9/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
A61K 31/4439 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
4439containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61P 1/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
CPC
A61K 31/4439
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
4439containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 33/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
44Elemental carbon, e.g. charcoal, carbon black
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 9/1688
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1682Processes
1688resulting in pure drug agglomerate optionally containing up to 5% of excipient
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applicants
  • OCERA THERAPEUTICS, INC. [US]/[US] (AllExceptUS)
  • FRAPAISE, Xavier [FR]/[US] (UsOnly)
Inventors
  • FRAPAISE, Xavier
Agents
  • HART, Daniel
Priority Data
60/838,93217.08.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF ADSBORBENT CARBON MICROSPHERES (AST-120) TO TREAT GASTROESOPHOGEAL REFLUX DISEASE OR SYMPTOMS THEREOF
(FR) UTILISATION DE MICROSPHÈRES DE CARBONE ADSORBANT (AST-120) POUR LE TRAITEMENT DU REFLUX GASTRO-ŒSOPHAGIEN (GERD) OU DES SYMPTÔMES DE CELUI-CI
Abstract
(EN)
Disclosed herein is the use of adsorbent carbon microspheres (AST-120, MP-146 or kremezin) to treat symptoms of GERD including heartburn, painful swallowing, chest pain, and for reducing bile content in the duodenum. The adsorbent carbon microspheres may be administered alone or in combination with a proton pumb inhibitor.
(FR)
La présente invention concerne l'utilisation de microsphères de carbone adsorbant (AST-120 ou MP-146 ou krémézine) pour le traitement des symptômes du reflux gastro-œsophagien (pyrosis, déglutition douloureuse, douleurs thoraciques) et pour diminuer la quantité de bile dans le duodénum. Les microsphères de carbone adsorbant peuvent s'administrer seules ou en association avec un inhibiteur de la pompe à protons.
Also published as
US20080089943
Latest bibliographic data on file with the International Bureau
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