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1. WO2008020364 - BIOCHEMICAL SENSOR DEVICE

Publication Number WO/2008/020364
Publication Date 21.02.2008
International Application No. PCT/IB2007/053116
International Filing Date 07.08.2007
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
C40B 30/04 2006.01
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
30Methods of screening libraries
04by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
CPC
G01N 33/5438
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
54373involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
5438Electrodes
Applicants
  • KONINKLIJKE PHILIPS ELECTRONICS N. V. [NL]/[NL] (AllExceptUS)
  • JOHNSON, Mark Thomas [GB]/[NL] (UsOnly)
  • STAPERT, Hendrik Roelof [NL]/[NL] (UsOnly)
  • GILLIES, Murray Fulton [GB]/[NL] (UsOnly)
  • PONJEE, Marc Wilhelmus Gijsbert [NL]/[NL] (UsOnly)
  • WIDDERSHOVEN, Franciscus Petrus [NL]/[NL] (UsOnly)
Inventors
  • JOHNSON, Mark Thomas
  • STAPERT, Hendrik Roelof
  • GILLIES, Murray Fulton
  • PONJEE, Marc Wilhelmus Gijsbert
  • WIDDERSHOVEN, Franciscus Petrus
Agents
  • SCHOUTEN, Marcus M.
Priority Data
06118874.414.08.2006EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIOCHEMICAL SENSOR DEVICE
(FR) CAPTEUR BIOCHIMIQUE
Abstract
(EN)
The present application relates to a biological sensor device comprising a biological sensing element and an electrode arrangement, the electrode arrangement comprising an electrode (101) and an electrode structure (103, 105, 107, 109), the electrode structure (103, 105, 107, 109) being arranged around the biological sensing element (201) and around the electrode (101). In array form, the device is used for carrying out high throughput biospecific binding assays, hybridization assays etc. Since the electrode structure allows electrophoretic or dielectrophoretic concentration of the target molecules at the sensing element, thereby overcoming diffusion limited binding kinetics.
(FR)
La présente invention concerne un capteur biochimique comprenant un élément capteur biologique et un dispositif d'électrode, le dispositif d'électrode comprenant une électrode (101) et une structure d'électrode (103, 105, 107, 109), la structure d'électrode (103, 105, 107, 109) étant disposée autour de l'élément capteur biologique (201) et autour de l'électrode (101).
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