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1. (WO2008007277) DETECTION OF ANALYTES IN A DUAL-MEDIATOR ELECTROCHEMICAL TEST STRIP
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2008/007277 International Application No.: PCT/IB2007/052474
Publication Date: 17.01.2008 International Filing Date: 26.06.2007
IPC:
C12Q 1/26 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
26
involving oxidoreductase
Applicants:
AGAMATRIX, INC. [US/US]; 10 Manor Parkway Salem, NH 03079, US (AllExceptUS)
HARDING, Ian [GB/US]; GB (UsOnly)
IYENGAR, Sridhar G. [US/US]; US (UsOnly)
Inventors:
HARDING, Ian; GB
IYENGAR, Sridhar G.; US
Agent:
LARSON, Marina T; Marina Larson & Associates, LLC PO Box 4928 Dillon, Colorado 80435, US
Priority Data:
60/805,91827.06.2006US
Title (EN) DETECTION OF ANALYTES IN A DUAL-MEDIATOR ELECTROCHEMICAL TEST STRIP
(FR) DÉTECTION D'ANALYTES DANS UNE BANDE DE TEST ÉLECTROCHIMIQUE À DEUX MÉDIATEURS
Abstract:
(EN) Determination of an analyte such as glucose in a sample is done making use of a plurality of electron transfer reagents, for example two electron transfer reagents, that work together to transfer electrons between the enzyme and the electrodes. The first electron transfer agent is a mediator that interacts with the enzyme after it has acted on the analyte to regenerate enzyme in its active form. The second electron transfer agent is a shuttle that interacts with the electrodes and optionally the mediator. The oxidation and reduction of the shuttle serves as the major source of current that is measured as an indication of analyte.
(FR) Selon l'invention, la détermination d'un analyte tel que le glucose présent dans un échantillon est effectuée en faisant usage d'une pluralité de réactifs de transfert d'électrons, par exemple de deux réactifs de transfert d'électrons, qui agissent ensemble pour transférer les électrons entre l'enzyme et les électrodes. Le premier agent de transfert d'électrons est un médiateur qui interagit avec l'enzyme après que celle-ci a agi sur l'analyte pour régénérer l'enzyme sous sa forme active. Le second agent de transfert d'électrons est une navette qui interagit avec les électrodes et éventuellement avec le médiateur. L'oxydation et la réduction de la navette servent de source principale du courant qui est mesuré en tant qu'indication de la quantité de l'analyte.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)