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1. WO2007149043 - ASSAY DEVICE

Publication Number WO/2007/149043
Publication Date 27.12.2007
International Application No. PCT/SE2007/050445
International Filing Date 20.06.2007
Chapter 2 Demand Filed 18.04.2008
IPC
G01N 33/558 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
558using diffusion or migration of antigen or antibody
CPC
B01L 2200/025
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
02Adapting objects or devices to another
025Align devices or objects to ensure defined positions relative to each other
B01L 2300/025
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
02Identification, exchange or storage of information
025Displaying results or values with integrated means
B01L 2300/0825
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0825Test strips
B01L 2300/087
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
087Multiple sequential chambers
B01L 2300/089
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
089Virtual walls for guiding liquids
B01L 2400/0406
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0403specific forces
0406capillary forces
Applicants
  • ÅMIC AB [SE]/[SE] (AllExceptUS)
  • ÖHMAN, Per Ove [SE]/[SE] (UsOnly)
  • MENDEL-HARTVIG, Ib [SE]/[SE] (UsOnly)
  • LINDSTROM, Tomas [SE]/[SE] (UsOnly)
Inventors
  • ÖHMAN, Per Ove
  • MENDEL-HARTVIG, Ib
  • LINDSTROM, Tomas
Agents
  • BERGENSTRÅHLE & LINDVALL AB
Priority Data
0601353-620.06.2006SE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ASSAY DEVICE
(FR) dispositif de test
Abstract
(EN)
The present invention provides an assay device for performing an assay on a liquid sample using a detection conjugate capable of binding to an antigen and containing a label, said device comprising a substrate having a substrate surface, wherein the surface comprises projections substantially perpendicular to said surface, said projections having a height, diameter and distance capable of generating lateral capillary flow of a fluid in said passage, said surface comprising a sample addition zone, a reaction zone and an absorbing zone, said zones being connected by at least one fluid passage, wherein said device has a first functionality verifying feature located between the sample addition zone and the reaction zone, and a second functionality verifying feature located within the absorbing zone, and both functionality verifying features being features capable of undergoing a detectable change when contacted by the sample, said assay device further comprising at least one alignment verification zone. There is further provided a kit of parts and a method of conducting an assay.
(FR)
La présente invention concerne un dispositif de test pour réaliser une détermination sur un échantillon liquide en utilisant un conjugué de détection capable de se lier à un antigène et contenant un marqueur, ledit dispositif comprenant un substrat qui présente une surface de substrat. La surface comprend des saillies essentiellement perpendiculaires à ladite surface, lesdites saillies ayant une hauteur, un diamètre et une distance conçus pour générer un écoulement globalement capillaire d'un fluide dans ledit passage, ladite surface comprenant une zone d'addition de l'échantillon, une zone de réaction et une zone d'absorption, lesdites zones étant reliées par au moins un passage d'écoulement. Ledit dispositif présente un premier élément de vérification de la fonctionnalité situé entre la zone d'addition de l'échantillon et la zone de réaction et un deuxième élément de vérification de la fonctionnalité situé dans la zone d'absorption, les deux éléments vérifiant les caractéristiques étant des éléments susceptibles de subir un changement détectable lorsqu'ils entrent en contact avec l'échantillon, ledit dispositif de test comprenant de plus au moins une zone de vérification de l'alignement. L'invention concerne de plus une trousse de pièces et un procédé pour effectuer une détermination.
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