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1. WO2007148363 - SALMONELLA ENTERICA STRAINS OF REDUCED PATHOGENICITY, METHOD FOR THEIR PREPARATION AND USES THEREOF

Publication Number WO/2007/148363
Publication Date 27.12.2007
International Application No. PCT/IT2007/000410
International Filing Date 08.06.2007
IPC
C12N 1/36 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
36Adaptation or attenuation of cells
A61K 35/74 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
CPC
A61K 2039/522
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
52Bacterial cells; Fungal cells; Protozoal cells
522avirulent or attenuated
A61K 2039/552
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
55characterised by the host/recipient, e.g. newborn with maternal antibodies
552Veterinary vaccine
A61K 35/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
A61K 39/0275
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
025Enterobacteriales, e.g. Enterobacter
0275Salmonella
C12N 1/36
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof
36Adaptation or attenuation of cells
Y02A 50/30
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50in human health protection
30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applicants
  • UNIVERSITA' DEGLI STUDI DI ROMA ''TOR VERGATA'' [IT]/[IT] (AllExceptUS)
  • INSTITUTO SUPERIORE DI SANITA' [IT]/[IT] (AllExceptUS)
  • AMMENDOLA, Serena [IT]/[IT] (UsOnly)
  • BATTISTONI, Andrea [IT]/[IT] (UsOnly)
  • PASQUALI, Paolo [IT]/[IT] (UsOnly)
Inventors
  • AMMENDOLA, Serena
  • BATTISTONI, Andrea
  • PASQUALI, Paolo
Agents
  • CALOGERO, Ida
Priority Data
RM2006A0032821.06.2006IT
Publication Language English (EN)
Filing Language Italian (IT)
Designated States
Title
(EN) SALMONELLA ENTERICA STRAINS OF REDUCED PATHOGENICITY, METHOD FOR THEIR PREPARATION AND USES THEREOF
(FR) SOUCHES DE SALMONELLA ENTERICA DE PATHOGENICITE REDUITE, PROCEDE PERMETTANT DE LES PREPARER ET LEURS UTILISATIONS
Abstract
(EN)
The invention concerns novel Salmonella enterica attenuated strains, characterized in that they are inactivated at the level of the znuABC operon through mutation in at least one of the znuA, znuB, znuC genes of such operon, for uses in medical or veterinary fields as vaccines.
(FR)
L'invention concerne de nouvelles souches atténuées de Salmonella enterica, caractérisées par le fait qu'elles sont inactivées au niveau de l'opéron znuABC par mutation un ou plusieurs des gènes znuA, znuB, znuC d'un tel opéron, pour des utilisations dans des domaines médicaux et vétérinaires comme vaccins.
Also published as
Latest bibliographic data on file with the International Bureau