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1. WO2007147748 - AQP5 POLYMORPHISM

Publication Number WO/2007/147748
Publication Date 27.12.2007
International Application No. PCT/EP2007/055731
International Filing Date 12.06.2007
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/118
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
118Prognosis of disease development
C12Q 2600/156
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
156Polymorphic or mutational markers
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
Applicants
  • UNIVERSITÄT DUISBURG-ESSEN [DE]/[DE] (AllExceptUS)
  • ADAMZIK, Michael [DE]/[DE] (UsOnly)
  • FREY, Ulrich [DE]/[DE] (UsOnly)
  • SIFFERT, Winfried [DE]/[DE] (UsOnly)
Inventors
  • ADAMZIK, Michael
  • FREY, Ulrich
  • SIFFERT, Winfried
Agents
  • COHAUSZ & FLORACK
Priority Data
10 2006 028 009.119.06.2006DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) AQP5-POLYMORPHISMUS
(EN) AQP5 POLYMORPHISM
(FR) POLYMORPHISME DE APQ5
Abstract
(DE)
Zur Vorhersage von Krankheitsrisiken, Krankheitsverläufen und des Ansprechens eines individuellen Patienten auf pharmakologische und nicht-pharmakologische Therapien, sucht man nach einem Polymorphismus im AQP5-Gen, insbesondere in der Promotorregion dieses Gens, auf dem Chromosom 12q13 des Menschen, wobei die Therapie auch eine kosmetische Behandlung sein kann.
(EN)
In order to predict disease risks, disease courses and the response of an individual patient to pharmacological and non-pharmacological therapies a polymorphism in the AQP5 gene has been investigated, in particular in the promoter region of said gene,on the human 12q13 chromosome, wherein the therapy can also be a cosmetic treatment.
(FR)
Pour prévoir les risques de maladies, l'évolution de maladies et la réaction d'un patient individuel à des thérapies pharmacologiques et non pharmacologiques, on recherche un polymorphisme dans le gène APQ5, notamment dans la région du promoteur de ce gène, sur le chromosome 12q13 chez l'homme. Selon l'invention, la thérapie peut également consister en un traitement cosmétique.
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