Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Saturday 31.10.2020 at 7:00 AM CET
Settings

Settings

Goto Application

1. WO2007145158 - HOLLOW-FIBER-LIKE ORGANIC NANOTUBE AND PROCESS FOR PRODUCTION THEREOF

Publication Number WO/2007/145158
Publication Date 21.12.2007
International Application No. PCT/JP2007/061703
International Filing Date 11.06.2007
IPC
B82B 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
3Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
A61K 8/60 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
60Sugars; Derivatives thereof
A61K 47/26 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 47/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42107; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
B01J 20/24 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
22comprising organic material
24Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
B01J 20/28 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
28characterised by their form or physical properties
CPC
A61K 47/6925
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
6921the form being a particulate, a powder, an adsorbate, a bead or a sphere
6925the form being a microcapsule, nanocapsule, microbubble or nanobubble
A61K 47/6929
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
6921the form being a particulate, a powder, an adsorbate, a bead or a sphere
6927the form being a solid microparticle having no hollow or gas-filled cores
6929the form being a nanoparticle, e.g. an immuno-nanoparticle
A61K 9/0092
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0087Galenical forms not covered by A61K9/02 - A61K9/7023
0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules, nanotubes
B01J 20/28007
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
28characterised by their form or physical properties
28002characterised by their physical properties
28004Sorbent size or size distribution, e.g. particle size
28007with size in the range 1-100 nanometers, e.g. nanosized particles, nanofibers, nanotubes, nanowires or the like
B01J 20/28014
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
28characterised by their form or physical properties
28014characterised by their form
B82Y 30/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
30Nanotechnology for materials or surface science, e.g. nanocomposites
Applicants
  • 独立行政法人産業技術総合研究所 NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY [JP]/[JP] (AllExceptUS)
  • 浅川 真澄 ASAKAWA, Masumi [JP]/[JP] (UsOnly)
  • 小木曽 真樹 KOGISO, Masaki [JP]/[JP] (UsOnly)
  • 神谷 昌子 KAMIYA, Shouko [JP]/[JP] (UsOnly)
  • 清水 敏美 SIMIZU, Toshimi [JP]/[JP] (UsOnly)
Inventors
  • 浅川 真澄 ASAKAWA, Masumi
  • 小木曽 真樹 KOGISO, Masaki
  • 神谷 昌子 KAMIYA, Shouko
  • 清水 敏美 SIMIZU, Toshimi
Priority Data
2006-16426914.06.2006JP
2006-17471326.06.2006JP
2007-13627723.05.2007JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) HOLLOW-FIBER-LIKE ORGANIC NANOTUBE AND PROCESS FOR PRODUCTION THEREOF
(FR) NANOTUBE organique en forme de fibre creuse et son procédé de fabrication
(JA) 中空繊維状有機ナノチューブ及びその製造方法
Abstract
(EN)
Disclosed is a process which can synthesize an organic nanotube capable of including a functional substance efficiently and free from water, in a simple manner and in a large quantity. The process comprises the steps of: causing the self-assembly of an N-glycoside-type glycolipid represented by the general formula (1) or a peptide lipid represented by the general formula (2) or (3) in a solution by (i) dissolving the N-glycoside-type glycolipid or the peptide lipid in an organic solvent heated to a temperature equal to or lower than the boiling point thereof, then cooling the solution gradually, and allowing the solution to stand at room temperature, (ii) dissolving the N-glycoside-type glycolipid or the peptide lipid in an organic solvent, condensing the solution, and allowing the condensed solution to stand at room temperature, or (iii) dissolving the N-glycoside-type glycolipid or the peptide lipid in an organic solvent heated to a temperature equal to or lower than the boiling point thereof, adding a poor solvent for the N-glycoside-type glycolipid or the peptide lipid to the solution, and allowing the solution to stand at room temperature, thereby producing a hollow-fiber-like organic nanotube; collecting the organic nanotube from the solution; and air-drying the organic nanotube at room temperature or drying the organic nanotube by heating under reduced pressure. G-NHCO-R1 (1) [wherein G represents a sugar residue produced by removing a hemiacetal hydroxyl group binding to an anomeric carbon atom in a sugar; and R1 represents an unsaturated hydrocarbon group having 10 to 39 carbon atoms] R2CO(NH-CHR3-CO)mOH (2) H(NH-CHR3-CO)mNHR2 (3) [wherein R2 represents a hydrocarbon group having 6 to 24 carbon atoms; R3 represents an amino acid side chain; and m represents an integer of 1 to 10]
(FR)
La présente invention concerne un procédé qui peut synthétiser un nanotube organique pouvant inclure une substance fonctionnelle de manière efficace et sans eau, simplement et en grandes quantités. Le procédé comprend les étapes consistant à : entraîner l'auto-assemblage d'un glycolipide du type N-glycoside représenté par la formule générale (1) ou d'un lipide peptidique représenté par la formule générale (2) ou (3) dans une solution (i) en dissolvant le glycolipide du type N-glycoside ou le lipide peptidique dans un solvant organique chauffé à une température inférieure ou égale au point d'ébullition de celui-ci, puis en refroidissant progressivement la solution, et en la laissant reposer à température ambiante, (ii) en dissolvant ledit glycolipide ou ledit lipide dans un solvant organique, en condensant la solution et en laissant la solution condensée reposer à température ambiante, ou (iii) en dissolvant ledit glycolipide ou ledit lipide dans un solvant organique chauffé à une température inférieure ou égale au point d'ébullition de celui-ci, en ajoutant un solvant faible pour ledit glycolipide ou ledit lipide à la solution, et en laissant la solution reposer à température ambiante, produisant ainsi un nanotube organique en forme de fibre creuse ; récupérer le nanotube organique à partir de la solution ; et sécher à l'air ledit nanotube à température ambiante ou le sécher en chauffant sous pression réduite. G-NHCO-R1 (1) [dans laquelle G représente un résidu de sucre produit en retirant un groupe hydroxyle hémiacétalique lié à un atome de carbone anomérique dans un sucre ; et R1 représente un groupe hydrocarboné insaturé comportant 10 à 39 atomes de carbone] R2CO(NH-CHR3-CO)mOH (2) H(NH-CHR3-CO)mNHR2 (3) [dans laquelle R2 représente un groupe hydrocarboné comportant 6 à 24 atomes de carbone ; R3 représente une chaîne latérale d'acides aminés ; et m représente un entier de 1 à 10]
(JA)
 機能性物質を効率的に包接することのできる、水分を全く含まない有機ナノチューブを簡便に大量合成する方法を提供するものであって、下記一般式(1) G-NHCO-R             (1) (式中、Gは糖のアノマー炭素原子に結合するヘミアセタール水酸基を除いた糖残基を表し、Rは炭素数が10~39の不飽和炭化水素基を表す。)表わされるN-グリコシド型糖脂質、又は下記一般式(2)又は(3) RCO(NH-CHR-CO)OH     (2) H(NH-CHR-CO)NHR      (3) (式中、Rは炭素数6~24の炭化水素基、Rはアミノ酸側鎖、mは1~10の整数を表す。)で表わされるペプチド脂質を、(i)沸点以下に加温された有機溶媒に溶解させ、その溶液を徐冷し、これを室温で静置するか、(ii)有機溶媒に溶解させ、その溶液を濃縮し、これを室温で静置するか、あるいは(iii)沸点以下に加温された有機溶媒に溶解させ、その溶液に該N-グリコシド型糖脂質又は該ペプチド脂質に対する貧溶媒を加え、これを室温で静置するか、のいずれかにより溶液中で自己集合することにより生成する中空繊維状有機ナノチューブを溶液から回収し、室温で風乾又は減圧加熱乾燥させ、中空繊維状有機ナノチューブを得る。  
Latest bibliographic data on file with the International Bureau