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1. WO2007142738 - COATINGS LAYERS FOR MEDICAL DEVICES AND METHODS OF MAKING THE SAME

Publication Number WO/2007/142738
Publication Date 13.12.2007
International Application No. PCT/US2007/009114
International Filing Date 13.04.2007
IPC
A61L 31/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31Materials for other surgical articles
08Materials for coatings
10Macromolecular materials
A61L 31/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31Materials for other surgical articles
14Materials characterised by their function or physical properties
16Biologically active materials, e.g. therapeutic substances
CPC
A61L 2300/406
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
404Biocides, antimicrobial agents, antiseptic agents
406Antibiotics
A61L 2300/41
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
41Anti-inflammatory agents, e.g. NSAIDs
A61L 2300/416
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
A61L 2300/606
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
60characterised by a special physical form
606Coatings
A61L 27/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
28Materials for coating prostheses
34Macromolecular materials
A61L 27/50
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
Applicants
  • ABBOTT CARDIOVASCULAR SYSTEMS INC. [US]/[US] (AllExceptUS)
  • LUDWIG, Florian N. [DE]/[US] (UsOnly)
  • HOSSAINY, Syed Faiyaz Ahmed [US]/[US] (UsOnly)
  • SRIDHARAN, Srinivasan [IN]/[US] (UsOnly)
  • LEE, Carol [US]/[US] (UsOnly)
Inventors
  • LUDWIG, Florian N.
  • HOSSAINY, Syed Faiyaz Ahmed
  • SRIDHARAN, Srinivasan
  • LEE, Carol
Agents
  • KERRIGAN, Cameron K.
Priority Data
11/445,04131.05.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COATINGS LAYERS FOR MEDICAL DEVICES AND METHODS OF MAKING THE SAME
(FR) COUCHES DE REVÊTEMENT POUR DISPOSITIFS MÉDICAUX ET PROCÉDÉS DE FABRICATION DE CELLES-CI
Abstract
(EN)
Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents.
(FR)
La présente invention concerne des procédés pour contrôler la morphologie et la vitesse de libération d'agent actif depuis des couches de revêtement pour des dispositifs médicaux comprenant une matrice de polymère et un ou plusieurs agents actifs. Les procédés comprennent la fixation de la morphologie ou de la distribution de phase de l'agent actif avant d'éliminer le solvant de la composition de revêtement. Les couches de revêtement peuvent être utilisées pour contrôler la libération d'un agent actif ou d'une combinaison d'agents actifs.
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