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1. WO2007142604 - MICRO THERMAL CYCLER WITH SELECTIVE HEAT ISOLATION

Publication Number WO/2007/142604
Publication Date 13.12.2007
International Application No. PCT/SG2007/000041
International Filing Date 08.02.2007
IPC
G01N 33/487 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
B01L 2300/0816
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
B01L 2300/0864
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0864comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
B01L 2300/0867
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0867Multiple inlets and one sample wells, e.g. mixing, dilution
B01L 2300/1805
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
18Means for temperature control
1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
B01L 2300/1822
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
18Means for temperature control
1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
1822using Peltier elements
B01L 2300/1883
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
18Means for temperature control
1883using thermal insulation
Applicants
  • NANYANG POLYTECHNIC [SG]/[SG] (AllExceptUS)
  • PRABHU, Vinayak Ashok [IN]/[SG] (UsOnly)
  • ONG, Hui Yng [MY]/[SG] (UsOnly)
  • YAP, Teck Boon Steven [SG]/[SG] (UsOnly)
Inventors
  • PRABHU, Vinayak Ashok
  • ONG, Hui Yng
  • YAP, Teck Boon Steven
Agents
  • LAWRENCE Y D HO & ASSOCIATES PTE LTD
Priority Data
200603945-709.06.2006SG
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MICRO THERMAL CYCLER WITH SELECTIVE HEAT ISOLATION
(FR) MICRO-CYCLEUR THERMIQUE AVEC ISOLATION THERMIQUE SÉLECTIVE
Abstract
(EN)
A temperature controller (10) for the reaction chambers of a microfluidic chip or lab on a chip is disclosed' with an insulator block (11) which supports the chip (not illustrated) and metallic heat conductors (12) positioned in vias in the insulating block that coincide with the positions of the reaction chambers of the microfluidic chip. Locking means (13) hold the chip in position. A cooling/heating block (14) such as a Peltier element provides the thermal changes which spreads by conduction up to the vias to heat the reaction chambers of the chip. A heat sink (15) with eg cooling fins dissipates unwanted heat.
(FR)
L'invention concerne un régulateur de température (10) pour les chambres de réaction d'une puce microfluidique ou d'un laboratoire sur puce comprenant un bloc d'isolant (11) qui supporte la puce (non illustrée) et des conducteurs de chaleur métalliques (12) positionnés dans des trous de liaison dans le bloc d'isolant qui coïncident avec les positions des chambres de réaction de la puce microfluidique. Des dispositifs de verrouillage (13) maintiennent la puce en position. Un bloc de refroidissement/chauffage (14) tel qu'un élément à effet Peltier crée les changements thermiques qui se propagent par conduction jusqu'aux trous de liaison pour chauffer les chambres de réaction de la puce. Un dissipateur thermique (15) avec par exemple des ailettes de refroidissement dissipe la chaleur indésirable.
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