Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2007133451) CANCELLOUS BONE TREATED WITH COLLEGENASE AND ESSENTIALLY FREE OF BLOOD CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2007/133451 International Application No.: PCT/US2007/010589
Publication Date: 22.11.2007 International Filing Date: 02.05.2007
Chapter 2 Demand Filed: 26.11.2007
IPC:
A61F 2/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Applicants:
WILLIAMS, Michelle, Le Roux [US/US]; US (UsOnly)
MILLS, Charles, Randal [US/US]; US (UsOnly)
MONROY, Rodney [US/US]; US (UsOnly)
NUVASIVE, INC. [US/US]; 7473 Lusk Boulevard San Diego, CA 92121, US (AllExceptUS)
Inventors:
WILLIAMS, Michelle, Le Roux; US
MILLS, Charles, Randal; US
MONROY, Rodney; US
Agent:
LILLIE, Raymond ; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein 5 Becker Farm Road Roseland, NJ 07068, US
Priority Data:
60/798,47408.05.2006US
60/831,72318.07.2006US
Title (EN) CANCELLOUS BONE TREATED WITH COLLEGENASE AND ESSENTIALLY FREE OF BLOOD CELLS
(FR) OS SPONGIEUX TRAITÉ AU COLLAGÉNASE ET ESSENTIELLEMENT DÉPOURVU DE CELLULES SANGUINES
Abstract:
(EN) A bone implant comprising cancellous bone that is essentially free of blood cells, and which has been treated with at least a loosening agent, such as collagenase and/or a digestive enzyme, for a time and at a concentration to loosen the osteogenic cells in the cancellous bone matrix. The osteogenic cells in the matrix are viable cells. The treatment of the cancellous bone with at least one loosening agent enables the osteogenic cells to be more available for carrying our their osteogenic function and to provide for an increased rate of bone formation.
(FR) Implant osseux à os spongieux essentiellement dépourvu de cellules sanguines, traité avec au moins un agent de desserrement, du type collagénase et/ou enzyme digestive, pendant une durée et selon une concentration données permettant le desserrement des cellules ostéogènes dans la matrice d'os spongieux. Les cellules ostéogènes de la matrice sont des cellules viables. Le traitement de l'os spongieux avec au moins un agent de desserrement permet une meilleure disponibilité des cellules ostéogènes dans l'exercice de leur fonction ostéogène et une augmentation du taux de formation osseuse.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)