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1. (WO2007110868) HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/110868    International Application No.:    PCT/IL2007/000404
Publication Date: 04.10.2007 International Filing Date: 28.03.2007
Chapter 2 Demand Filed:    21.05.2008    
IPC:
C07D 239/90 (2006.01), C07D 403/06 (2006.01), C07D 403/12 (2006.01), C07D 405/06 (2006.01), C07D 405/12 (2006.01), C07D 471/04 (2006.01), C07D 311/22 (2006.01), C07D 473/06 (2006.01), C07D 401/06 (2006.01), C07D 473/30 (2006.01), C07D 401/12 (2006.01), C07D 413/06 (2006.01), A61K 31/517 (2006.01), C07D 417/12 (2006.01), A61K 31/4523 (2006.01)
Applicants: ATIR HOLDING S.A. [LU/LU]; 23 Aldringen Street, L-1118 Luxembourg (LU) (For All Designated States Except US).
TWOROWSKI, Dmitry [IL/IL]; (IL) (For US Only).
MATSIEVITCH, Ron [IL/IL]; (IL) (For US Only).
KOGAN, Vladimir [IL/IL]; (IL) (For US Only)
Inventors: TWOROWSKI, Dmitry; (IL).
MATSIEVITCH, Ron; (IL).
KOGAN, Vladimir; (IL)
Agent: G. E. EHRLICH (1995) LTD.; 11 Menachem Begin Street, 52521 Ramat Gan (IL)
Priority Data:
60/786,379 28.03.2006 US
60/879,531 10.01.2007 US
Title (EN) HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS
(FR) COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS DANS LE TRAITEMENT DE TROUBLES SEXUELS
Abstract: front page image
(EN)Novel heterocyclic compounds, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.
(FR)La présente invention concerne des nouveaux composés hétérocycliques, qui présentent une activité agonistique de récepteur de dopamine (de préférence un récepteur D4), et/ou une activité d'inhibition de PDE5, leurs procédés de préparation, des compositions pharmaceutiques les contenant et leurs utilisations dans le traitement de troubles sexuels tels qu'une diminution de la libido, un trouble de l'orgasme et un problème d'érection.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)