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Machine translation
1. (WO2007098267) PSEUDOINFECTIOUS FLAVIVIRUS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/098267    International Application No.:    PCT/US2007/004957
Publication Date: 30.08.2007 International Filing Date: 27.02.2007
IPC:
A61K 39/12 (2006.01), C12N 7/00 (2006.01), C12N 5/00 (2006.01)
Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 West Seventh Street, Austin, TX 78701 (US) (For All Designated States Except US)
Inventors: FROLOV, Ilya; (US).
FROLOVA, Elena; (US).
MASON, Peter, C.; (US)
Agent: ADLER, Benjamin, A.; Adler & Associates, 8011 Candle Lane, Houston, TX 77071 (US)
Priority Data:
60/777,189 27.02.2006 US
Title (EN) PSEUDOINFECTIOUS FLAVIVIRUS AND USES THEREOF
(FR) FLAVIVIRUS PSEUDO-INFECTIEUX ET SES UTILISATIONS
Abstract: front page image
(EN)The present invention discloses a replication-deficient pseudoinfective virus belonging to the Flaviviridae family that lack the capsid gene, where the replication- deficient pseudoinfective virus propagates only in cells expressing the capsid or capsid, prM and envelope protein of the flavivirus. The present also discloses the method of producing such viruses on a large scale and the use of these pseudoinfective viruses as vaccines for preventing diseases caused by infections of humans or animals by the viruses belonging to this family.
(FR)La présente invention concerne un virus pseudo-infectieux défectueux de réplication qui appartient à la famille des Flaviviridae, auquel manque le gène de capside, lequel virus pseudo-infectieux défectueux de réplication se propage uniquement dans des cellules qui expriment la capside ou les protéines prM et d'enveloppe de capside du flavivirus. Elle concerne aussi la méthode pour produire de tels virus à grande échelle et pour utiliser lesdits virus pseudo-infectieux comme vaccins pour prévenir des maladies causées par des infections d'êtres humains ou d'animaux par des virus appartenant à cette famille.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)