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Pub. No.:    WO/2007/097317    International Application No.:    PCT/JP2007/053066
Publication Date: 30.08.2007 International Filing Date: 20.02.2007
C07D 239/84 (2006.01), A61K 31/517 (2006.01), A61P 17/00 (2006.01), A61P 17/04 (2006.01), A61P 37/08 (2006.01)
Applicants: Eisai R & D Management Co., Ltd. [JP/JP]; 6-10, Koishikawa 4-chome, Bunkyo-ku, Tokyo 1128088 (JP) (For All Designated States Except US).
MIYAZAKI, Kazuki [JP/JP]; (JP) (For US Only).
KUSANO, Kazutomi [JP/JP]; (JP) (For US Only).
TAKASE, Yasutaka [JP/JP]; (JP) (For US Only).
ASANO, Osamu [JP/JP]; (JP) (For US Only).
SHIRATO, Manabu [JP/JP]; (JP) (For US Only).
WAKITA, Hisashi [JP/JP]; (JP) (For US Only).
ISHII, Naoto [JP/JP]; (JP) (For US Only).
SAEKI, Takao [JP/JP]; (JP) (For US Only)
Inventors: MIYAZAKI, Kazuki; (JP).
KUSANO, Kazutomi; (JP).
TAKASE, Yasutaka; (JP).
ASANO, Osamu; (JP).
SHIRATO, Manabu; (JP).
WAKITA, Hisashi; (JP).
ISHII, Naoto; (JP).
SAEKI, Takao; (JP)
Agent: HASEGAWA, Yoshiki; SOEI PATENT AND LAW FIRM Ginza First Bldg. 10-6, Ginza 1-chome Chuo-ku, Tokyo 1040061 (JP)
Priority Data:
2006-043273 21.02.2006 JP
(JA) 4-(3-ベンゾイルアミノフェニル)-6,7-ジメトキシ-2-メチルアミノキナゾリン誘導体
Abstract: front page image
(EN)A compound represented by the formula (I) below, a salt thereof or a hydrate of any of them is capable of effectively suppressing itch of atopic diseases and the like. (I) [In the formula, R represents a hydroxyl group, a C1-6 alkoxy group which may be substituted by a C1-6 alkoxy group, or an amino group which may be substituted by a C1-6 alkyl group.]
(FR)La présente invention concerne un composé représenté par la formule (I) ci-dessous, un sel de celui-ci ou un hydrate de l'un de ceux-ci, capable de supprimer efficacement le prurit lié aux maladies atopiques et analogues. (I) [Dans la formule, R représente un groupe hydroxyle, un groupe alkoxy en C1-6 pouvant être substitué par un groupe alkoxy en C1-6, ou un groupe amino pouvant être substitué par un groupe alkyle en C1-6.]
(JA)not available
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)