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1. (WO2007096782) COMPOSITIONS FOR DISORDERS ASSOCIATED WTTH METACHROMATIC CELL ACTIVATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/096782    International Application No.:    PCT/IB2007/001621
Publication Date: 30.08.2007 International Filing Date: 22.02.2007
IPC:
A61K 31/137 (2006.01), A61K 31/353 (2006.01), A61K 31/4409 (2006.01), A61K 31/445 (2006.01), A61K 31/519 (2006.01), A61K 31/5377 (2006.01), A61K 31/573 (2006.01), A61P 11/00 (2006.01), A61P 11/06 (2006.01), A61P 29/00 (2006.01), A61P 37/08 (2006.01), A61P 43/00 (2006.01)
Applicants: VALORISATION RECHERCHE HSCM, LIMITED PARTNERSHIP [CA/CA]; 5160 Decarie, Suite 770 Montreal, Quebec, H3X 2H9 (CA) (For All Designated States Except US).
MAGHNI, Karim [FR/CA]; (CA) (For US Only).
OUAKED, Nadia [CA/CA]; (CA) (For US Only).
LEFORT, Bertrand [FR/CA]; (CA) (For US Only).
FAVRET, Sandra [FR/CA]; (CA) (For US Only)
Inventors: MAGHNI, Karim; (CA).
OUAKED, Nadia; (CA).
LEFORT, Bertrand; (CA).
FAVRET, Sandra; (CA)
Agent: ROBINSON, Christopher, J.; Smart & Biggar, Box 11560 Vancouver Centre, Suite 2200, 650 West Georgia Street, Vancouver, British Columbia V6B 4N8 (CA)
Priority Data:
60/775,324 22.02.2006 US
Title (EN) COMPOSITIONS FOR DISORDERS ASSOCIATED WTTH METACHROMATIC CELL ACTIVATION
(FR) COMPOSÉS ET PROCÉDÉS DESTINÉS AU TRAITEMENT DE TROUBLES ASSOCIÉS À L'ACTIVATION DES CELLULES MÉTACHROMATIQUES
Abstract: front page image
(EN)The present invention relates to neurokinin- 1 (NK-1) receptor antagonists in combination with an inhibitor of metachromatic cell activation, such as an anti- inflammatory agent, an immunosuppressor, or a kinase inhibitor, and use of such combinations in the treatment of disorders associated with activation of metachromatic cells. Disorders associated with the activation of metachromatic cells include allergic/non-allergic rhinitis, allergic/non-allergic asthma, allergic/non-allergic urticaria, immuno-infiammatory disorders, metachromatic cell-related autoimmune disorders, transplant rejection, and other metachromatic cell-related disorders.
(FR)L'invention concerne des antagonistes récepteur de la neurokinine-1 (NK-1) en combinaison avec un inhibiteur d'activation des cellules métachromatiques, tel qu'un anti-inflammatoire, un immunosuppresseur, ou un inhibiteur de kinase, et l'utilisation de ces combinaisons dans le traitement de troubles associés à l'activation des cellules métachromatiques. Les troubles associés à l'activation des cellules métachromatiques sont notamment la rhinite allergique/non allergique, l'asthme allergique/non allergique, l'urticaire allergique/non allergique, les troubles immuno-inflammatoires, les troubles auto-immuns associés aux cellules métachromatiques, le rejet de greffe, et d'autres troubles associés aux cellules métachromatiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)