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1. WO2007096055 - COMBINATION OF SOMATOSTATIN-ANALOGS WITH DIFFERENT SELECTIVITY FOR HUMAN SOMATOSTATIN RECEPTOR SUBTYPES

Publication Number WO/2007/096055
Publication Date 30.08.2007
International Application No. PCT/EP2007/001036
International Filing Date 07.02.2007
Chapter 2 Demand Filed 24.10.2007
IPC
A61K 38/31 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
31Somatostatins
CPC
A61K 38/31
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
31Somatostatins
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
12Antidiarrhoeals
A61P 1/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
18for pancreatic disorders, e.g. pancreatic enzymes
A61P 11/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
16Central respiratory analeptics
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
Applicants
  • NOVARTIS, AG [CH]/[CH] (AllExceptUS)
  • SCHMID, Herbert [DE]/[DE] (UsOnly)
Inventors
  • SCHMID, Herbert
Agents
  • GRAFF, Alan
Priority Data
0602639.709.02.2006GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMBINATION OF SOMATOSTATIN-ANALOGS WITH DIFFERENT SELECTIVITY FOR HUMAN SOMATOSTATIN RECEPTOR SUBTYPES
(FR) COMBINAISON D'ANALOGUES DE LA SOMATOSTATINE PRESENTANT UNE SELECTIVITE DIFFERENTE POUR CHACUN DES SOUS-TYPES DE RECEPTEURS DE LA SOMATOSTATINE HUMAINE
Abstract
(EN)
The present invention relates to a combination of two or more Somatostatin (SRIF) peptidomimetics (also referred to as Somatostatin- or SRIF-analogs) which have different selectivity for the human somatostatin receptor subtypes SSTR2 and SSTR5, the use of such combination in the treatment of a disease mediated by activation of somatostatin receptors, and to pharmaceutical compositions comprising such a combination.
(FR)
La présente invention concerne une combinaison de deux ou plusieurs peptidomimétiques de la somatostatine (ou Somatotropin Release Inhibiting Factor ; SRIF), également appelés analogues de la somatostatine ou analogues du SRIF, lesdits peptidomimétiques présentant une sélectivité différente pour chacun des cinq sous-types de récepteurs de la somatostatine humaine. L'invention concerne également l'utilisation d'une telle combinaison pour le traitement d'une maladie induite par l'activation des récepteurs de la somatostatine et des compositions pharmaceutiquement qui comprennent une telle combinaison.
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