WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007095747) CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD59
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/095747    International Application No.:    PCT/CA2007/000280
Publication Date: 30.08.2007 International Filing Date: 22.02.2007
IPC:
C07K 16/28 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01), C12P 21/08 (2006.01), G01N 33/574 (2006.01)
Applicants: ARIUS RESEARCH INC. [CA/CA]; (CA).
YOUNG, David S.F.; (CA) (For US Only).
FINDLAY, Helen, P.; (CA) (For US Only).
HAHN, Susan, E.; (CA) (For US Only).
CECHETTO, Lisa, M.; (CA) (For US Only).
DaCRUZ, Luis, A. G.; (CA) (For US Only)
Inventors: YOUNG, David S.F.; (CA).
FINDLAY, Helen, P.; (CA).
HAHN, Susan, E.; (CA).
CECHETTO, Lisa, M.; (CA).
DaCRUZ, Luis, A. G.; (CA)
Agent: SINGLEHURST, John, C.; Finlayson & Singlehurst, 70 Gloucester Street, Ottawa, Ontario K2P 0A2 (CA)
Priority Data:
11/361,153 24.02.2006 US
Title (EN) CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD59
(FR) MÉDIATION DE CYTOTOXICITÉ DE CELLULES METTANT EN ÉVIDENCE L'EXPRESSION SUPERFICIELLE DE CD59
Abstract: front page image
(EN)This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumour cells evidencing surface expression of CD59, and to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response The invention further relates to binding assays which utilize the CDMAB of the instant invention.
(FR)L'invention concerne le diagnostic et le traitement de maladies cancéreuses, notamment la médiation de cytotoxicité de cellules tumorales mettant en évidence l'expression superficielle de CD59, et l'utilisation d'anticorps modifiant les maladies cancéreuses (CDMAB), éventuellement en combinaison avec un ou plusieurs agents chimiothérapeutiques, en tant que moyens destinés à amorcer la réponse cytotoxique. L'invention concerne en outre des dosages de liaison qui utilisent ces CDMAB.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)