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1. (WO2007095536) TREATMENT AND PREVENTION OF RENAL DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/095536    International Application No.:    PCT/US2007/062065
Publication Date: 23.08.2007 International Filing Date: 13.02.2007
IPC:
A61K 31/19 (2006.01)
Applicants: MOUNT SINAI SCHOOL OF MEDICINE [US/US]; 1425 Madison Avenue, New York, NY 10029 (US) (For All Designated States Except US).
ROSS, Michael, J. [US/US]; (US) (For US Only).
KLOTMAN, Paul, E. [US/US]; (US) (For US Only).
KLOTMAN, Mary, E. [US/US]; (US) (For US Only)
Inventors: ROSS, Michael, J.; (US).
KLOTMAN, Paul, E.; (US).
KLOTMAN, Mary, E.; (US)
Agent: TISCHNER, Tate, L.; Nixon Peabody LLP, Clinton Square, P.o. Box 31051, Rochester, NY 14603-1051 (US)
Priority Data:
60/772,753 13.02.2006 US
Title (EN) TREATMENT AND PREVENTION OF RENAL DISEASE
(FR) TRAITEMENT ET PREVENTION DE MALADIES RENALES
Abstract: front page image
(EN)The present invention is directed to a method of treating or preventing renal disease in a subject. This method involves administering the subject an agent which inhibits FAT10 expression in the subject under conditions effective to prevent or treat renal disease. Also disclosed is a method of screening for agents effective in treating or preventing renal disease.
(FR)La présente invention concerne un procédé destiné au traitement ou à la prévention de maladies rénales chez un sujet. Ce procédé consiste à administrer au sujet un agent qui inhibe l'expression du FAT10 chez ce dernier dans des conditions suffisamment efficaces pour pouvoir prévenir ou traiter une maladie rénale. L'invention porte également sur un procédé de criblage destiné aux agents permettant de traiter ou de prévenir efficacement une maladie rénale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)