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Machine translation
1. (WO2007095202) BLOCKADE OF GAMMA-SECRETASE ACTIVITY TO PROMOTE MYELINATION BY OLIGODENDROCYTES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/095202    International Application No.:    PCT/US2007/003725
Publication Date: 23.08.2007 International Filing Date: 13.02.2007
IPC:
C12N 5/079 (2010.01)
Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY [US/US]; 1705 El Camino Real, Palo Alto, California 94306-1106 (US) (For All Designated States Except US).
WATKINS, Trent Alan [US/US]; (US) (For US Only).
BARRES, Ben A. [US/US]; (US) (For US Only)
Inventors: WATKINS, Trent Alan; (US).
BARRES, Ben A.; (US)
Agent: SHERWOOD, Pamela J.; Bozicevic, Field & Francis Llp, 1900 University Avenue, Suite 200, East Palo Alto, California 94303 (US)
Priority Data:
60/773,191 13.02.2006 US
Title (EN) BLOCKADE OF GAMMA-SECRETASE ACTIVITY TO PROMOTE MYELINATION BY OLIGODENDROCYTES
(FR) BLOCAGE DE L'ACTIVITÉ DE LA GAMMA-SÉCRÉTASE POUR FAVORISER LA MYÉLINISATION PAR LES OLIGODENDROCYTES
Abstract: front page image
(EN)Methods are provided for enhancing myelination. Myelination is enhanced by administration of agents that are inhibitors of ϝ-secretase. Methods of screening for pharmaceutically active compounds that enhance myelination, and for genes involved in myelination are also provided.
(FR)L'invention concerne des procédés de renforcement de la myélinisation. La myélinisation est renforcée par l'administration d'agents qui sont des inhibiteurs de la &ggr;-sécrétase. La présente invention concerne également des procédés de criblage de composés pharmaceutiquement actifs qui renforcent la myélinisation ainsi que de gènes impliqués dans la myélinisation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)