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Machine translation
1. (WO2007094754) THERAPEUTIC MONOCLONAL ANTIBODIES THAT NEUTRALIZE BOTULINUM NEUROTOXINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/094754    International Application No.:    PCT/US2006/003070
Publication Date: 23.08.2007 International Filing Date: 26.01.2006
IPC:
A61K 39/40 (2006.01), G01N 33/554 (2006.01), G01N 33/569 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORDNIA [US/US]; 1111 Franklin Street, 12th Floor, Oakland, CA 94607-5200 (US) (For All Designated States Except US).
MARKS, James, D. [US/US]; (US) (For US Only).
AMERSDORFER, Peter [US/US]; (US) (For US Only).
GEREN, Isin [US/US]; (US) (For US Only).
LOU, Jianlong [US/US]; (US) (For US Only).
RAZAI, Ali [US/US]; (US) (For US Only).
GARCIA, Maria, Consuelos [US/US]; (US) (For US Only)
Inventors: MARKS, James, D.; (US).
AMERSDORFER, Peter; (US).
GEREN, Isin; (US).
LOU, Jianlong; (US).
RAZAI, Ali; (US).
GARCIA, Maria, Consuelos; (US)
Agent: HUNTER, Tom; Beyer Weaver LLP, P.O. Box 70250, Oakland, CA 94612-0250 (US)
Priority Data:
60/648,256 27.01.2005 US
Title (EN) THERAPEUTIC MONOCLONAL ANTIBODIES THAT NEUTRALIZE BOTULINUM NEUROTOXINS
(FR) ANTICORPS MONOCLONAUX THÉRAPEUTIQUES NEUTRALISANT LES NEUROTOXINES BOTULIQUES
Abstract: front page image
(EN)This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/ A) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
(FR)La présente invention concerne des anticorps qui se lient spécifiquement à et neutralisent la neurotoxine botulique de type A (BoNT/A), ainsi que les épitopes liés par ces anticorps. Ces anticorps et leurs dérivés et/ou d'autres anticorps qui se lient spécifiquement aux épitopes neutralisants selon l'invention peuvent être utilisés pour neutraliser la neurotoxine botulique et sont donc utiles dans le traitement du botulisme.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)