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1. (WO2007094548) BERBERRUBINE DERIVATIVES HAVING ANTIFUNGAL ACTIVITIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/094548    International Application No.:    PCT/KR2006/004607
Publication Date: 23.08.2007 International Filing Date: 06.11.2006
IPC:
C07D 455/03 (2006.01), A61K 31/4375 (2006.01)
Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY [KR/KR]; 52 Eoeun-dong, Yuseong-gu, Daejeon 305-806 (KR) (For All Designated States Except US).
KIM, Sung Uk [KR/KR]; (KR) (For US Only).
PARK, Ki Duk [KR/KR]; (KR) (For US Only).
MOON, Jae Sun [KR/KR]; (KR) (For US Only).
KANG, Tae Hoon [KR/KR]; (KR) (For US Only).
KIM, Young-Kook [KR/KR]; (KR) (For US Only)
Inventors: KIM, Sung Uk; (KR).
PARK, Ki Duk; (KR).
MOON, Jae Sun; (KR).
KANG, Tae Hoon; (KR).
KIM, Young-Kook; (KR)
Agent: PAIK, Nam-Hoon; 14th Fl., KTB Network Building 826-14, Yeoksam-dong, Kangnam-ku, Seoul 135-769 (KR)
Priority Data:
10-2006-0014146 14.02.2006 KR
Title (EN) BERBERRUBINE DERIVATIVES HAVING ANTIFUNGAL ACTIVITIES
(FR) DÉRIVÉS DE BERBERRUBINE À ACTIVITÉS ANTIFONGIQUES
Abstract: front page image
(EN)The present invention relates to a berberrubine derivative having superior antifungal activity, more particularly to a berberrubine derivative having inhibitory activity against chitin synthase, which participates in the synthesis of chitin and is essential in the growth of fungi, and having a potent antifungal activity against human pathogenic fungi.
(FR)La présente invention concerne un dérivé de berberrubine possédant une activité antifongique supérieure, plus spécifiquement, un dérivé de berberrubine à activité inhibitrice contre la chitine synthase qui participe à la synthèse de la chitine et est essentielle à la croissance de champignons. Ledit dérivé de berberrubine a une puissante activité antifongique contre les champignons pathogènes humains.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)