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1. (WO2007094340) VASODILATOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/094340    International Application No.:    PCT/JP2007/052569
Publication Date: 23.08.2007 International Filing Date: 14.02.2007
Chapter 2 Demand Filed:    13.12.2007    
IPC:
A61K 38/00 (2006.01), A61P 9/08 (2006.01), A61P 9/10 (2006.01)
Applicants: CALPIS CO., LTD. [JP/JP]; 4-1, Ebisu-Minami 2-chome, Shibuya-ku, Tokyo 1500022 (JP) (For All Designated States Except US).
HIROTA, Tatsuhiko [JP/JP]; (JP) (For US Only).
OHKI, Kohji [JP/JP]; (JP) (For US Only)
Inventors: HIROTA, Tatsuhiko; (JP).
OHKI, Kohji; (JP)
Agent: SAKAI, Hajime; Nihon Jitensha Kaikan 9-15, Akasaka 1-chome Minato-ku, Tokyo 107-0052 (JP)
Priority Data:
2006-035944 14.02.2006 JP
Title (EN) VASODILATOR
(FR) VASODILATATEUR
(JA) 血管拡張剤
Abstract: front page image
(EN)It is intended to provide a vasodilator having a vascular endothelium-dependent vasodilating action, a preventive agent for arteriosclerosis, and a functional food having a vascular endothelium-dependent vasodilating action which can be continuously used on a daily basis and is excellent in safety. The vasodilator and the functional food of the invention are characterized by comprising, as an active ingredient, at least one of tripeptides of Val Pro Pro and Ile Pro Pro or a protein degradation product containing Val Pro Pro and/or Ile Pro Pro.
(FR)L'invention concerne un vasodilatateur ayant une action vasodilatatrice dépendant de l'endothélium vasculaire, un agent préventif de l'artériosclérose et un aliment fonctionnel ayant une action vasodilatatrice dépendant de l'endothélium vasculaire qui peut être utilisé de façon continue quotidiennement et présente une excellente inoquité. Le vasodilatateur et l'aliment fonctionnel de l'invention sont caractérisés en ce qu'ils comprennent, en tant que principe actif, un tripeptide Val Pro Pro et/ou Ile Pro Pro ou un produit de dégradation de protéine contenant Val Pro Pro et/ou Ile Pro Pro.
(JA)血管内皮依存性の血管拡張作用を有する血管拡張剤、動脈硬化予防剤及び日常的に連用可能で、安全性に優れ、血管内皮依存性の血管拡張作用を有する機能性食品を提供すること。本発明の血管拡張剤及び機能性食品は、Val Pro Pro及びIle Pro Proの少なくとも1つのトリペプチド又は、Val Pro Pro及び/又はIle Pro Proを含有する蛋白質分解物を有効成分として含むことを特徴とする。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)