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Machine translation
1. (WO2007093901) 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/093901    International Application No.:    PCT/IB2007/000368
Publication Date: 23.08.2007 International Filing Date: 05.02.2007
IPC:
C07D 471/04 (2006.01), A61K 31/435 (2006.01), A61K 31/495 (2006.01), C07D 213/80 (2006.01), C07D 213/75 (2006.01)
Applicants: PFIZER LIMITED [GB/GB]; Ramsgate Road, Sandwich, Kent CT13 9NJ (GB) (For All Designated States Except US).
JONES, Peter [GB/GB]; (GB) (For US Only).
PRYDE, David, Cameron [GB/GB]; (GB) (For US Only).
TRAN, Thien Duc [FR/GB]; (GB) (For US Only)
Inventors: JONES, Peter; (GB).
PRYDE, David, Cameron; (GB).
TRAN, Thien Duc; (GB)
Agent: DROUIN, Stéphane; Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ (GB)
Priority Data:
60/774,580 17.02.2006 US
60/829,730 17.10.2006 US
60/870,020 14.12.2006 US
Title (EN) 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS
(FR) DÉRIVÉS DE 3-DÉAZAPURINE EN TANT QUE MODULATEURS DE TLR7
Abstract: front page image
(EN)The present invention relates to immune response modifiers of Formula (I), which act selectively through agonism, of Toll-Like Receptors (TLRs), uses thereof, processes for the preparation thereof, intermediates used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious disease such as Hepatitis (e.g. HCV, HBV), genetically related viral infection and cancer.
(FR)La présente invention concerne des agents modifiant la réponse immunitaire de formule (I), qui agissent sélectivement par agonisme des récepteurs analogues à Toll (TLR, Toll-like receptor), leurs utilisations, des procédés pour les préparer, des intermédiaires utilisés pour les préparer et des compositions contenant lesdits inhibiteurs. Ces inhibiteurs sont utiles dans divers domaines thérapeutiques, parmi lesquels le traitement d'une maladie infectieuse telle que l'hépatite (par exemple HCV, HBV), une infection par un virus génétiquement apparenté et le cancer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)