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1. (WO2007093819) DNA CONFORMATION (LOOP STRUCTURES) IN NORMAL AND ABNORMAL GENE EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/093819    International Application No.:    PCT/GB2007/000564
Publication Date: 23.08.2007 International Filing Date: 19.02.2007
IPC:
C12Q 1/68 (2006.01)
Applicants: ISIS INNOVATION LIMITED [GB/GB]; Ewert House, Ewert Place, Summertown, Oxford OX2 7SG (GB) (For All Designated States Except US).
AKOULITCHEV, Alexandre [GB/GB]; (GB) (For US Only).
RAMADASS, Aroul, Selvam [GB/GB]; (GB) (For US Only).
NIKITENKO, Leonid, Leonidovich [GB/GB]; (GB) (For US Only)
Inventors: AKOULITCHEV, Alexandre; (GB).
RAMADASS, Aroul, Selvam; (GB).
NIKITENKO, Leonid, Leonidovich; (GB)
Agent: ROQUES, Sarah, Elizabeth; J.A. Kemp & Co., 14 South Square, Gray's Inn, London WC1R 5JJ (GB)
Priority Data:
0603251.0 17.02.2006 GB
Title (EN) DNA CONFORMATION (LOOP STRUCTURES) IN NORMAL AND ABNORMAL GENE EXPRESSION
(FR) CONFORMATION D'ADN
Abstract: front page image
(EN)Method of detection or diagnosis of abnormal gene expression in an individual comprising determining in a sample from the individual the presence or absence of a chromosome structure in which two separate regions of the gene have been brought into close proximity, to thereby detect or diagnose whether the individual has abnormal gene expression.
(FR)Procédé de détection ou de diagnostic d'une expression génique anormale chez un individu, comprenant la détermination, dans un échantillon provenant de cet individu, de la présence ou de l'absence d'une structure chromosomique dans laquelle deux régions séparées du gène ont été amenées à proximité étroite l'une de l'autre afin de détecter ou de diagnostiquer ainsi l'existence d'une expression génique anormale chez ledit individu.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)