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Pub. No.:    WO/2007/093542    International Application No.:    PCT/EP2007/051165
Publication Date: 23.08.2007 International Filing Date: 07.02.2007
Chapter 2 Demand Filed:    16.08.2007    
C07D 213/81 (2006.01), C07D 239/42 (2006.01), C07D 417/12 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 403/12 (2006.01), C07D 417/14 (2006.01), A61K 31/443 (2006.01), A61K 31/444 (2006.01), A61K 31/4436 (2006.01), A61K 31/4439 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH) (For All Designated States Except US).
JAESCHKE, Georg [DE/CH]; (CH) (For US Only).
SPOOREN, Will [DK/FR]; (FR) (For US Only).
VIEIRA, Eric [CH/CH]; (CH) (For US Only)
Inventors: JAESCHKE, Georg; (CH).
SPOOREN, Will; (FR).
VIEIRA, Eric; (CH)
Agent: BANHOLZER, Vivien; Grenzacherstrasse 124, CH-4070 Basel (CH)
Priority Data:
06110086.3 17.02.2006 EP
Abstract: front page image
(EN)The present invention relates to novel pyridine-2-carboxyamide derivatives of the general formula (I) useful as metabotropic glutamate receptor antagonists: (I) wherein Y, Z, R1, R2 and R3 are as defined in the specification herein.
(FR)La présente invention concerne de nouveaux dérivés de pyridine-2-carboxamide de formule générale (I) qui peuvent être employés en tant qu'antagonistes du récepteur métabotropique du glutamate : (I) où Y, Z, R1, R2 et R3 sont tels que définis dans la description de l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)