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1. WO2007092574 - CRYSTALLINE FORMS OF CICLESONIDE

Publication Number WO/2007/092574
Publication Date 16.08.2007
International Application No. PCT/US2007/003405
International Filing Date 07.02.2007
IPC
C07J 71/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
71Steroids in which the cyclopentahydrophenanthrene skeleton is condensed with a heterocyclic ring
A61K 31/58 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
A61P 11/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
CPC
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 3/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
06Antihyperlipidemics
A61P 9/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
C07J 71/0031
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
71Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
0005Oxygen-containing hetero ring
0026cyclic ketals
0031at positions 16, 17
Applicants
  • SICOR, INC. [US]/[US] (AllExceptUS)
  • ROSSETTO, Pierluigi [IT]/[CH] (UsOnly)
  • MACDONALD, Peter, Lindsay [AU]/[CH] (UsOnly)
  • LEVI, Sigalit [IL]/[IL] (UsOnly)
  • ARONHIME, Judith [IL]/[IL] (UsOnly)
Inventors
  • ROSSETTO, Pierluigi
  • MACDONALD, Peter, Lindsay
  • LEVI, Sigalit
  • ARONHIME, Judith
Agents
  • PUCKETT, Craig, L.
Priority Data
60/771,65408.02.2006US
60/773,84115.02.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CRYSTALLINE FORMS OF CICLESONIDE
(FR) FORMES CRISTALLINES DE CICLESONIDE
Abstract
(EN)
The invention encompasses a crystalline form of ciclesonide characterized by an XRD pattern having peaks at about 1 1.0, 14.8, 15.7, 16.5, and 22.8 degrees two-theta ± 0.2 degrees two-theta, methods of its preparation and pharmaceutical compositions thereof. Formula (I).
(FR)
La présente invention concerne une forme cristalline de ciclésonide caractérisée par un diagramme de diffraction des rayons X ayant des pics à environ 11,0, 14,8, 15,7, 16,5 et 22,8 degrés deux-thêta ± 0,2 degré deux-thêta, ses procédés de préparation et des compositions pharmaceutiques de celle-ci.
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