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1. WO2007091066 - APPLICATIONS OF NON-INTEGRATING LENTIVIRAL VECTORS

Publication Number WO/2007/091066
Publication Date 16.08.2007
International Application No. PCT/GB2007/000431
International Filing Date 07.02.2007
IPC
C12N 15/867 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
86Viral vectors
867Retroviral vectors
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
CPC
C12N 15/86
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
86Viral vectors
C12N 2740/16043
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2740Reverse Transcribing RNA Viruses
00011Reverse Transcribing RNA Viruses
10011Retroviridae
16011Human Immunodeficiency Virus, HIV
16041Use of virus, viral particle or viral elements as a vector
16043viral genome or elements thereof as genetic vector
Applicants
  • UCL BUSINESS PLC [GB]/[GB] (AllExceptUS)
  • YANEZ-MUNOZ, Rafael, Joaquin [ES]/[GB] (UsOnly)
  • THRASHER, Adrian [GB]/[GB] (UsOnly)
  • ALI, Robin [GB]/[GB] (UsOnly)
Inventors
  • YANEZ-MUNOZ, Rafael, Joaquin
  • THRASHER, Adrian
  • ALI, Robin
Agents
  • BRADY, Paul, Andrew
Priority Data
60/771,17107.02.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) APPLICATIONS OF NON-INTEGRATING LENTIVIRAL VECTORS
(FR) APPLICATIONS DE VECTEURS LENTIVIRAUX NON INTÉGRANTS
Abstract
(EN)
This invention provides a method of gene therapy comprising administering to a subject an integration-deficient lentiviral vector containing a nucleic acid that provides benefit.
(FR)
La présente invention concerne un procédé de thérapie génique comprenant l'administration à un sujet d'un vecteur lentiviral à déficience d'intégration contenant un acide nucléique bénéfique.
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