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1. (WO2007091059) PREPARATION AND COMPOSITION OF A SOLID DOSAGE FORM CONTAINING TACROLIMUS AND/OR SIROLIMUS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/091059    International Application No.:    PCT/GB2007/000422
Publication Date: 16.08.2007 International Filing Date: 06.02.2007
Chapter 2 Demand Filed:    30.08.2007    
IPC:
A61K 9/20 (2006.01), A61K 9/48 (2006.01), A61K 31/436 (2006.01)
Applicants: PLIVA HRVATSKA D.O.O. [HR/HR]; Ulica grada Vukovara 49, 10000 Zagreb (HR) (For All Designated States Except US).
FRANC, Ales [CZ/CZ]; (CZ) (For US Only).
ZALUDEK, Borek [CZ/CZ]; (CZ) (For US Only).
GONEC, Roman [CZ/CZ]; (CZ) (For US Only).
CIRKVA, Ales [CZ/CZ]; (CZ) (For US Only).
MALOVANA, Sabina [CZ/CZ]; (CZ) (For US Only).
PETROVICOVA, Anna [CZ/CZ]; (CZ) (For US Only).
MCLEISH, Nicholas, Alistair, Maxwell [GB/GB]; (GB) (LR only)
Inventors: FRANC, Ales; (CZ).
ZALUDEK, Borek; (CZ).
GONEC, Roman; (CZ).
CIRKVA, Ales; (CZ).
MALOVANA, Sabina; (CZ).
PETROVICOVA, Anna; (CZ)
Agent: MCLEISH, Nicholas, Alistair, Maxwell; Boult Wade Tennant, Verulam Gardens, 70 Gray's Inn Road, London WC1X 8BT (GB)
Priority Data:
0602632.2 08.02.2006 GB
Title (EN) PREPARATION AND COMPOSITION OF A SOLID DOSAGE FORM CONTAINING TACROLIMUS AND/OR SIROLIMUS
(FR) PRÉPARATION ET COMPOSITION D'UNE FORME POSOLOGIQUE SOLIDE CONTENANT DU TACROLIMUS ET/OU DU SIROLIMUS
Abstract: front page image
(EN)A method is provided for preparing a solid dosage form comprising a water-insoluble medicinally active substance selected from tacrolimus and sirolimus, whereby the medicinally active substance is dissolved in an organic solvent, a mixture comprising at least one pharmaceutically acceptable carrier with swelling ability is then coated with the solvent containing the medicinally active substance, the solvent is evaporated, and the mixture is processed into a suitable solid dosage form.
(FR)La présente invention concerne un procédé de préparation d'une forme posologique d'une substance hydrosoluble à activité médicinale choisie parmi le tacrolimus et le sirolimus, selon lequel la substance à activité médicinale est dissoute dans un solvant organique, un mélange comprenant au moins un support pharmaceutiquement acceptable avec une capacité de gonflement est ensuite enrobé avec le solvant contenant la substance à activité médicinale, le solvant est évaporé, et le mélange est transformé en une forme posologique solide appropriée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)