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Machine translation
1. (WO2007090409) USE OF KCNQ-OPENERS FOR THREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/090409    International Application No.:    PCT/DK2007/050013
Publication Date: 16.08.2007 International Filing Date: 02.02.2007
IPC:
A61K 31/136 (2006.01), A61K 31/167 (2006.01), A61K 31/44 (2006.01), A61K 31/505 (2006.01), A61K 31/506 (2006.01), A61P 25/18 (2006.01)
Applicants: H. LUNDBECK A/S [DK/DK]; Ottiliavej 9, DK-2500 Valby-copenhagen (DK) (For All Designated States Except US).
HUSUM BAK-JENSEN, Henriette [DK/DK]; (DK) (For US Only).
WENZEL TORNØE, Christian [DK/DK]; (DK) (For US Only).
ROTTLÄNDER, Mario [DE/DK]; (DK) (For US Only).
GREVE, Daniel Rodriguez [DK/DK]; (DK) (For US Only).
KHANZHIN, Nikolay [RU/DK]; (DK) (For US Only).
RITZÉN, Andreas [SE/DK]; (DK) (For US Only).
WATSON, William Patrick [GB/DK]; (DK) (For US Only)
Inventors: HUSUM BAK-JENSEN, Henriette; (DK).
WENZEL TORNØE, Christian; (DK).
ROTTLÄNDER, Mario; (DK).
GREVE, Daniel Rodriguez; (DK).
KHANZHIN, Nikolay; (DK).
RITZÉN, Andreas; (DK).
WATSON, William Patrick; (DK)
Common
Representative:
H. LUNDBECK A/S; Ottiliavej 9, DK-2500 Valby-copenhagen (DK)
Priority Data:
PA 2006 00175 07.02.2006 DK
60/771,304 07.02.2006 US
Title (EN) USE OF KCNQ-OPENERS FOR THREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA
(FR) UTILISATION D'OUVREURS KCNQ POUR TRAITER OU RÉDUIRE DES SYMPTÔMES DE SCHIZOPHRÉNIE
Abstract: front page image
(EN)The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symtoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.
(FR)L'invention a pour objet une nouvelle méthode pour traiter ou réduire les symptômes de schizophrénie, qui consiste à administrer à un hôte la nécessitant une quantité efficace d'un composé capable d'augmenter sélectivement le flux d'ions à travers des canaux potassiques 5 KCNQ. En outre, l'invention concerne l'utilisation d'ouvreurs sélectifs de canaux potassiques KCNQ pour préparer une composition pharmaceutique permettant de traiter ou de réduire les symptômes de la schizophrénie et des symptômes, troubles et maladies apparentés. En outre l'invention concerne une méthode de criblage pour un composé ouvreur sélectif d'un canal potassique KCNQ, capable de posséder un potentiel anti-psychotique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)