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Pub. No.:    WO/2007/089731    International Application No.:    PCT/US2007/002452
Publication Date: 09.08.2007 International Filing Date: 29.01.2007
G01N 33/48 (2006.01)
Applicants: GEORGE MASON UNIVERSITY [US/US]; Office Of Technology Transfer, MSN 5G5, 4400 University Drive, Fairfax, VA 22030 (US) (For All Designated States Except US).
LIOTTA, Lance [--/US]; (US) (For US Only).
ZHOU, Weidong [--/US]; (US) (For US Only).
ESPINA, Virginia [--/US]; (US) (For US Only).
PETRICOIN, Emanuel [--/US]; (US) (For US Only)
Inventors: LIOTTA, Lance; (US).
ZHOU, Weidong; (US).
ESPINA, Virginia; (US).
PETRICOIN, Emanuel; (US)
Agent: ZELANO, Anthony J.; Millen, White, Zelano & Branigan, P.C., 2200 Clarendon Boulevard, Suite 1400, Arlington, VA 22201 (US)
Priority Data:
60/762,499 27.01.2006 US
Abstract: front page image
(EN)The present invention relates to the analysis and monitoring of ocular fluids for determining the physiological state of an organism, to monitor drug efficacy and dynamics, for early disease detection, as well as to certain molecular markers and fingerprints of identified molecules or molecule fragments in such analysis.
(FR)La présente invention concerne l'analyse et le contrôle de liquides oculaires visant à déterminer l'état physiologique d'un organisme, à contrôler l'efficacité et le comportement dynamique d'un médicament pour une détection précoce d'une maladie. Elle concerne également certains marqueurs moléculaires et empreintes digitales de molécules ou de fragments de molécules identifiés au cours de cette analyse.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)