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1. WO2007089685 - COMPOSITIONS AND METHODS FOR INDUCING ADIPOSE TISSUE CELL DEATH

Publication Number WO/2007/089685
Publication Date 09.08.2007
International Application No. PCT/US2007/002362
International Filing Date 30.01.2007
IPC
A61K 36/8962 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
8962Allium, e.g. garden onion, leek, garlic or chives
A61K 36/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
C07C 321/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
321Thiols, sulfides, hydropolysulfides or polysulfides
12Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
18of an acyclic unsaturated carbon skeleton
A61K 31/201 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
20having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
201having one or two double bonds, e.g. oleic or linoleic acid
CPC
A61K 31/704
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034attached to a carbocyclic compound, e.g. phloridzin
704attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
A61K 36/8962
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
8962Allium, e.g. garden onion, leek, garlic or chives
Applicants
  • UNIVERSITY OF GEORGIA RESEARCH FOUNDATION [US]/[US] (AllExceptUS)
  • DELLA-FERA, Mary, Anne [US]/[US] (UsOnly)
  • BAILE, Clifton, A. [US]/[US] (UsOnly)
  • YANG, Jeong-Yeh [KR]/[US] (UsOnly)
Inventors
  • DELLA-FERA, Mary, Anne
  • BAILE, Clifton, A.
  • YANG, Jeong-Yeh
Agents
  • LINDER, Christopher, B.
Priority Data
60/763,31030.01.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR INDUCING ADIPOSE TISSUE CELL DEATH
(FR) COMPOSITIONS ET MÉTHODES POUR INDUIRE UNE MORT CELLULAIRE DE TISSU ADIPEUX
Abstract
(EN)
Compositions and methods of inducing apoptosis in adipocyte tissue cells, treating obesity, including cell death of bone marrow adipocytes, and treating osteoporosis in host are provided. The said compositions comprise at least one garlic extract compound in combination with at least one conjugated linoleic acid.
(FR)
L'invention concerne des compositions et des méthodes permettant d'induire une apoptose dans des cellules de tissu d'adipocytes, de traiter une obésité, d'induire une mort cellulaire d'adipocytes de la moëlle osseuse, et de traiter une ostéoporose chez un hôte.
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