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1. WO2007089673 - COMPOSITIONS AND METHODS FOR TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS

Publication Number WO/2007/089673
Publication Date 09.08.2007
International Application No. PCT/US2007/002330
International Filing Date 26.01.2007
IPC
A61K 31/21 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
A61K 31/215 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
A61K 31/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
CPC
A61K 31/137
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
135having aromatic rings ; , e.g. ketamine, nortriptyline
137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine ; or methadone
Applicants
  • ACUCELA, INC. [US]/[US] (AllExceptUS)
  • KUBOTA, Ryo [JP]/[US] (UsOnly)
  • FAWZI, Ahmad [US]/[US] (UsOnly)
  • SCOTT, Ian, Leslie [US]/[US] (UsOnly)
  • KUKSA, Vladimir A. [RU]/[US] (UsOnly)
Inventors
  • KUBOTA, Ryo
  • FAWZI, Ahmad
  • SCOTT, Ian, Leslie
  • KUKSA, Vladimir A.
Agents
  • ROSOK, Mae, Joanne
Priority Data
60/762,38426.01.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS
(FR) COMPOSITIONS ET MÉTHODES DE TRAITEMENT POUR MALADIES ET TROUBLES OPHTALMIQUES
Abstract
(EN)
Provided herein are compositions and methods for treating ophthalmic diseases and disorders. Compositions comprising retinylamine derivative compounds provided herein are useful for treating and preventing ophthalmic diseases and disorders, including diabetic retinopathy diabetic maculopathy, diabetic macular edema, retinal ischemia, ischemia-reperfusion related retinal injury, and metabolic optic neuropathy.
(FR)
L'invention concerne des compositions et des méthodes pour traiter des maladies et des troubles ophtalmiques. Lesdites compositions comprennent des composés dérivés de la rétinylamine et sont utilisées pour traiter et prévenir des maladies et des troubles ophtalmiques, y compris une rétinopathie diabétique, une maculopathie diabétique, un œdème maculaire diabétique, une ischémie rétinienne, une lésion rétinienne d'ischémie de reperfusion, et une neuropathie optique métabolique.
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