WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007089587) MECHANICALLY INDUCED TRAPPING OF MOLECULAR INTERACTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/089587    International Application No.:    PCT/US2007/002176
Publication Date: 09.08.2007 International Filing Date: 26.01.2007
IPC:
G01N 33/53 (2006.01), C12Q 1/68 (2006.01)
Applicants: CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 East California Boulevard, M/C 210/85, Pasadena, California 91125 (US) (For All Designated States Except US).
MAERKL, Sebastian, J. [DE/US]; (US) (For US Only).
QUAKE, Stephen, R. [US/US]; (US) (For US Only)
Inventors: MAERKL, Sebastian, J.; (US).
QUAKE, Stephen, R.; (US)
Agent: APPLE, Randolph, T.; Townsend And Townsend And Crew LLP, Two Embarcadero Center, 8th Floor, San Francisco, California 94111-3834 (US)
Priority Data:
60/762,330 26.01.2006 US
60/762,344 26.01.2006 US
60/880,156 11.01.2007 US
60/880,209 11.01.2007 US
Title (EN) MECHANICALLY INDUCED TRAPPING OF MOLECULAR INTERACTIONS
(FR) PIEGEAGE MÉCANIQUE D'INTERACTIONS MOLÉCULAIRES
Abstract: front page image
(EN)The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.
(FR)L'invention concerne des dispositifs et des procédés de modélisation de surface du substrat d'un dispositif microfluidique, et de détection et d'analyse d'interactions entre des molécules par piègeage mécanique d'un complexe moléculaire tout en expulsant sensiblement un solvant et des molécules de solutés libres. Les exemples de complexes moléculaires comprennent des complexes protéine-protéine et des complexes protéine-acide nucléique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)