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1. (WO2007089513) TUMOR VASCULATURE MARKERS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/089513    International Application No.:    PCT/US2007/001959
Publication Date: 09.08.2007 International Filing Date: 25.01.2007
IPC:
C12Q 1/68 (2006.01), G01N 33/574 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street, Suite 200, Philadelphia, PA 19104-6283 (US) (For All Designated States Except US).
COUKOS, George [IT/US]; (US) (For US Only).
BUCKANOVICH, Ronald, J. [US/US]; (US) (For US Only).
GIMOTTY, Phyllis, A. [US/US]; (US) (For US Only)
Inventors: COUKOS, George; (US).
BUCKANOVICH, Ronald, J.; (US).
GIMOTTY, Phyllis, A.; (US)
Agent: COHEN, Mark, S.; PEARL COHEN ZEDEK LATZER, LLP, 1500 Broadway, 12th Floor, New York, NY 10036 (US)
Priority Data:
60/762,787 26.01.2006 US
60/791,212 12.04.2006 US
60/844,347 14.09.2006 US
Title (EN) TUMOR VASCULATURE MARKERS AND METHODS OF USE THEREOF
(FR) MARQUEURS DE SYSTÈME VASCULAIRE TUMORAL ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)This invention provides methods of detecting and localizing tumor vasculature cells (TVC) and solid tumors; and treating, impeding vascularization of, and determining the stage of solid tumors in a subject, comprising the step of contacting a subject or a TVC with a ligand that binds to a nucleic acid molecule of the present invention, or binds to a protein encoded by the nucleic acid molecule.
(FR)La présente invention concerne des procédés de détection et localisation de cellules de système vasculaire tumoral et de tumeurs solides; et le traitement, la prévention de la vascularisation, et la stadification de tumeurs solides chez un sujet, comprenant l'étape de mise en contact d'un sujet ou d'une cellule de système vasculaire tumoral avec un ligand se liant à une molécule d'acide nucléique de la présente invention, ou se liant à une protéine codée par la molécule d'acide nucléique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)