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Machine translation
1. (WO2007089303) METHODS AND COMPOSITIONS FOR DIAGNOSING ANKYLOSING SPONDYLITIS USING BIOMARKERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/089303    International Application No.:    PCT/US2006/042564
Publication Date: 09.08.2007 International Filing Date: 31.10.2006
Chapter 2 Demand Filed:    31.05.2007    
IPC:
C12Q 1/37 (2006.01), G01N 33/50 (2006.01), G01N 33/543 (2006.01), G01N 33/564 (2006.01), G01N 33/573 (2006.01), G01N 33/68 (2006.01)
Applicants: ABBOTT BIOTECHNOLOGY LTD. [GB/--]; Clarendon House, 2 Church Street, Hamilton HM 11 (BM) (For All Designated States Except US).
MAKSYMOWYCH, Walter, P. [CA/CA]; (CA) (For US Only).
WONG, Robert, L. [US/US]; (US) (For US Only)
Inventors: MAKSYMOWYCH, Walter, P.; (CA).
WONG, Robert, L.; (US)
Agent: DECONTI, Giulio, A.; Lahive & Cockfield, Llp, One Post Office Square, Boston, MA 02109-2127 (US)
Priority Data:
60/732,444 01.11.2005 US
Title (EN) METHODS AND COMPOSITIONS FOR DIAGNOSING ANKYLOSING SPONDYLITIS USING BIOMARKERS
(FR) MÉTHODES ET COMPOSITIONS DE DIAGNOSTIC DE LA SPONDYLARTHRITE ANKYLOSANTE À L'AIDE DE BIOMARQUEURS
Abstract: front page image
(EN)The invention provides a method for determining the efficacy of a TNFα inhibitor, such as a TNFα antibody, or an antigen-binding portion thereof, for treating ankylosing spondylitis (AS), using a collagen degradation biomarker and/or a synovitis biomarker.
(FR)L'invention porte sur une méthode déterminant l'efficacité d'un inhibiteur du TNFα, tel qu'un anticorps anti TNFα ou l'un de ses fragments, se fixant à un se fixant à un antigène, pour traiter la spondylarthrite ankylosante à l'aide d'un biomarqueur de dégradation du collagène, ou d'un biomarqueur de la synovite.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)