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Machine translation
1. (WO2007088489) PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/088489    International Application No.:    PCT/IB2007/001691
Publication Date: 09.08.2007 International Filing Date: 11.01.2007
IPC:
A61K 31/4748 (2006.01)
Applicants: HARROGATE HOLDINGS [GB/GB]; Canon's Court, 22 Victoria Street, Hamilton, Bermuda, HM 12 (GB) (For All Designated States Except US)
Inventors: ROYDS, Robert, B.; (US)
Priority Data:
11/346,657 03.02.2006 US
Title (EN) PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME
(FR) PRÉPARATION PHARMACEUTIQUE CONTENANT: UN AGONISTE OPIOÏDE CENTRAL, UN ANTAGONISTE OPIOÏDE CENTRAL, ET UN ANTAGONISTE OPIOÏDE PÉRIPHÉRIQUE, ET SA MÉTHODE D'OBTENTION
Abstract: front page image
(EN)A pharmaceutical composition for treating or preventing a disease, condition or symptoms thereof in a warm-blooded animal including a human, includes a therapeutically effective amount of an opioid agonist exhibiting potential pharmacologically addictive properties in warm blooded animals including humans; a side-effect reducing agent present in amounts sufficient to at least substantially neutralize the adverse side effects of the opioid agonist; an opioid antagonist present in a sequestered form in amounts sufficient to block the pharmacological effect of the opioid agonist upon release from the sequestered form; and a pharmaceutically acceptable carrier.
(FR)L'invention porte sur une préparation pharmaceutique de traitement ou prévention d'une maladie ou un état ou de leurs symptômes chez les animaux à sang chaud dont l'homme, contenant: une quantité à effet thérapeutique d'un agoniste opioïde aux propriétés pharmacologiques potentiellement toxicomanogènes; un agent réducteur des effets secondaires en quantité suffisante pour neutraliser au moins sensiblement les effets secondaires adverses de l'agoniste opioïde; un antagoniste opioïde présent sous forme séquestrée en quantité suffisante pour bloquer l'effet pharmacologique de l'agoniste opioïde lors de sa libération; et un excipient pharmacocompatible.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)