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Machine translation
1. (WO2007088345) THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/088345    International Application No.:    PCT/GB2007/000310
Publication Date: 09.08.2007 International Filing Date: 30.01.2007
IPC:
C07D 495/04 (2006.01), A61K 31/4365 (2006.01)
Applicants: UCB PHARMA S.A. [BE/BE]; 60 Allée De La Recherche, B-1070 Brussels (BE) (For All Designated States Except US).
HUTCHINGS, Martin, Clive [GB/GB]; (GB) (For US Only).
ARCHIBALD, Sarah, Catherine [GB/GB]; (GB) (For US Only).
BROOKINGS, Daniel, Christopher [GB/GB]; (GB) (For US Only).
DAVIS, Jeremy, Martin [GB/GB]; (GB) (For US Only).
JOHNSON, James, Andrew [GB/GB]; (GB) (For US Only).
LANGHAM, Barry, John [GB/GB]; (GB) (For US Only).
NEUSS, Judi, Charlotte [GB/GB]; (GB) (For US Only)
Inventors: HUTCHINGS, Martin, Clive; (GB).
ARCHIBALD, Sarah, Catherine; (GB).
BROOKINGS, Daniel, Christopher; (GB).
DAVIS, Jeremy, Martin; (GB).
JOHNSON, James, Andrew; (GB).
LANGHAM, Barry, John; (GB).
NEUSS, Judi, Charlotte; (GB)
Agent: THOMPSON, John; UCB Celltech, 208 Bath Road, Slough, Berkshire SL1 3WE (GB)
Priority Data:
0601962.4 31.01.2006 GB
Title (EN) THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS
(FR) DERIVES DE THIENO-PYRIDINE EN TANT QU'INHIBITEURS DE MEK
Abstract: front page image
(EN)A series of thieno[2,3-b]pyridine derivatives which are substituted in the 2- position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.
(FR)La présente invention concerne une série de dérivés de thiéno[2,3-b]pyridine qui portent une substitution en position 2 par un fragment anilino substitué. Lesdits dérivés sont des inhibiteurs sélectifs des enzymes MEK (MAPKK) humaines et ils présentent donc un intérêt en médecine, par exemple pour le traitement d'états inflammatoires, auto-immunitaires, cardio-vasculaires, prolifératifs (y compris oncologiques) et nociceptifs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)