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1. WO2007088189 - BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN

Publication Number WO/2007/088189
Publication Date 09.08.2007
International Application No. PCT/EP2007/050991
International Filing Date 01.02.2007
IPC
C07D 209/64 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
56Ring systems containing three or more rings
58- or -condensed
62Naphtho pyrroles; Hydrogenated naphtho pyrroles
64with an oxygen atom in position 1
C07D 209/66 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
56Ring systems containing three or more rings
58- or -condensed
62Naphtho pyrroles; Hydrogenated naphtho pyrroles
66with oxygen atoms in positions 1 and 3
A61K 31/4035 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
4035Isoindoles, e.g. phthalimide
A61P 25/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
02for peripheral neuropathies
CPC
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
10Laxatives
A61P 1/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
12Antidiarrhoeals
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
Applicants
  • GLAXO GROUP LIMITED [GB]/[GB] (AllExceptUS)
  • HEALY, Mark, Patrick [GB]/[GB] (UsOnly)
  • GIBLIN, Gerard, Martin, Paul [GB]/[GB] (UsOnly)
  • PRICE, Helen, Susanne [GB]/[GB] (UsOnly)
Inventors
  • HEALY, Mark, Patrick
  • GIBLIN, Gerard, Martin, Paul
  • PRICE, Helen, Susanne
Agents
  • KING, Lawrence
Priority Data
0602238.803.02.2006GB
0615094.028.07.2006GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN
(FR) DÉRIVÉS DE BENZOISOINDOLE UTILISÉS DANS LE TRAITEMENT DE LA DOULEUR
Abstract
(EN)
A compound of formula (I) or a pharmaceutically acceptable derivative thereof, wherein, R1, R2, R3, X and Y are as defined in the specification; a process for preparing such compounds; a pharmaceutical composition comprising such compounds; and the use of such compounds in medicine.
(FR)
La présente invention concerne un composé de formule (I) ou un dérivé de qualité pharmaceutique dudit composé, R1, R2, R3, X et Y étant tels que définis dans la description ; un procédé de synthèse de tels composés ; une préparation pharmaceutique incluant de tels composés ; et l'emploi de tels composés en médecine.
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